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verrucosidin

 
National Institutes of Health

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Pyrones

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2016
2016
An Unusual Conformational Isomer of Verrucosidin Backbone from a Hydrothermal Vent Fungus, Penicillium sp. Y-50-10
A new verrucosidin derivative, methyl isoverrucosidinol (1), was isolated from the marine fungus Penicillium sp. Y-50-10… Expand
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2016
2016
Biosynthetic Pathway of the Reduced Polyketide Product Citreoviridin in Aspergillus terreus var. aureus Revealed by Heterologous Expression in Aspergillus nidulans.
Citreoviridin (1) belongs to a class of F1-ATPase β-subunit inhibitors that are synthesized by highly reducing polyketide… Expand
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2013
2013
Repositioning of Verrucosidin, a Purported Inhibitor of Chaperone Protein GRP78, as an Inhibitor of Mitochondrial Electron Transport Chain Complex I
Verrucosidin (VCD) belongs to a group of fungal metabolites that were identified in screening programs to detect molecules that… Expand
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2012
2012
Duplex real-time PCR method with internal amplification control for quantification of verrucosidin producing molds in dry-ripened foods.
Verrucosidin, which is a tremorgenic mycotoxin responsible for neurological diseases, has been detected in different dry-ripened… Expand
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2007
2007
Glucose-deprived HT-29 human colon carcinoma cells are sensitive to verrucosidin as a GRP78 down-regulator.
Glucose deprivation, a feature of poorly vascularized solid tumors, activates the unfolded protein response (UPR) which is a… Expand
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2005
2005
Deoxyverrucosidin, a Novel GRP78/BiP Down-regulator, Produced by Penicillium sp.
Glucose-regulated protein 78 (GRP78) resides in endoplasmic reticulum (ER) and plays a role in protecting tumor cells against the… Expand
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2003
2003
Genotoxicity assessment of five tremorgenic mycotoxins (fumitremorgen B, paxilline, penitrem A, verruculogen, and verrucosidin) produced by molds isolated from fermented meats.
A number of toxinogenic fungal species, particularly producers of tremorgenic mycotoxins, have been isolated from traditional… Expand
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2000
2000
Effects of substrate, water activity, and temperature on growth and verrucosidin production by Penicillium polonicum isolated from dry-cured ham.
Penicillium polonicum, a common mold on dry-cured meat products, is able to produce verrucosidin, a potent neurotoxin. The… Expand
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Highly Cited
1999
Highly Cited
1999
Production of mycotoxins on artificially and naturally infested building materials
In this study, the ability to produce mycotoxins during growth on artificially infested building materials was investigated for… Expand
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1988
1988
Verrucofortine, a major metabolite of Penicillium verrucosum var. cyclopium, the fungus that produces the mycotoxin verrucosidin.
Verrucofortine [8], an alkaloid derived from tryptophan and leucine, has been isolated from the fungus Penicillium verrucosum var… Expand
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