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valyl-tyrosyl-prolyl-isoaspartyl-glycyl-alanine

Known as: Val-Tyr-Pro-isoAsp-Gly-Ala 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Oligopeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Profiling the 'deamidome' of complex biosamples using mixed-mode chromatography-coupled tandem mass spectrometry.
Deamidation is a spontaneous degenerative protein modification (DPM) that disrupts the structure and function of both endogenous… Expand
2013
2013
Interconversion of the peptide isoforms of aspartate: Stability of isoaspartates
A common modification of human long-lived proteins is spontaneous isomerisation of aspartate residues, and its biological… Expand
2012
2012
Structural and activity changes in three bioactive anuran peptides when Asp is replaced by isoAsp
The Asp and isoAsp isomers of three bioactive peptides, Crinia angiotensin 11 [APGDRIYHPF(OH)], uperin 1.1 [pEADPNAFYGLM(NH(2… Expand
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Highly Cited
2012
Highly Cited
2012
Racemization of two proteins over our lifespan: deamidation of asparagine 76 in γS crystallin is greater in cataract than in normal lenses across the age range.
PURPOSE Long-lived proteins are widespread in man, yet little is known about the processes that affect their function over time… Expand
Highly Cited
2005
Highly Cited
2005
Hydroxytyrosol, a natural antioxidant from olive oil, prevents protein damage induced by long-wave ultraviolet radiation in melanoma cells.
Previous studies showed that long-wave ultraviolet (UVA) radiation induces severe skin damage through the generation of reactive… Expand
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Highly Cited
2004
Highly Cited
2004
Chemical Pathways of Peptide Degradation. II. Kinetics of Deamidation of an Asparaginyl Residue in a Model Hexapeptide
Deamidation of Asn residues is a major chemical pathway of degradation of peptides and proteins. To understand better the… Expand
2003
2003
Quantification of the isomerization of Asp residue in recombinant human alpha A-crystallin by reversed-phase HPLC.
A method for determining the isomerization of Asp residues in proteins is described and demonstrated by quantifying the… Expand
Highly Cited
2000
Highly Cited
2000
Isoaspartate in peptides and proteins: formation, significance, and analysis.
Formation of isoaspartyl peptide bonds (isoAsp) is one of the most common forms of non-enzymatic degradation of peptides and… Expand
Highly Cited
2000
Highly Cited
2000
Analysis of isoaspartate in peptides by electrospray tandem mass spectrometry
In view of the significance of Asn deamidation and Asp isomerization to isoAsp at certain sites for protein aging and turnover… Expand
1996
1996
Synthesis of stereoisomers and isoforms of a tryptic heptapeptide fragment of human growth hormone and analysis by reverse-phase HPLC and capillary electrophoresis.
The amino acid sequence Asn-Gly has at pH 7 a tendency to induce deamidation of asparagine to aspartic acid via the formation of… Expand
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