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valyl-tyrosyl-prolyl-isoaspartyl-glycyl-alanine

Known as: Val-Tyr-Pro-isoAsp-Gly-Ala 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
01219962018

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Related topics

1 relation

Broader (1)

Oligopeptides

Related mentions per year

Related mentions per year

1954-2018
1960198020002020
valyl-tyrosyl-prolyl-isoaspartyl-glycyl-alanine
Oligopeptides

Papers overview

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2018
2018
Differences in α-Crystallin isomerization reveal the activity of protein isoaspartyl methyltransferase (PIMT) in the nucleus and cortex of human lenses.
Although it is well-known that protein turnover essentially stops in mature lens fiber cells, mapping out the ensuing protein… (More)
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2016
2016
Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset?
Multiple sclerosis (MS) is associated with breakdown of the myelin sheath that coats neurons in the central nervous system. The… (More)
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2013
2013
Interconversion of the peptide isoforms of aspartate: stability of isoaspartates.
A common modification of human long-lived proteins is spontaneous isomerisation of aspartate residues, and its biological… (More)
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2012
2012
Structural and activity changes in three bioactive anuran peptides when Asp is replaced by isoAsp.
The Asp and isoAsp isomers of three bioactive peptides, Crinia angiotensin 11 [APGDRIYHPF(OH)], uperin 1.1 [pEADPNAFYGLM(NH(2… (More)
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2012
2012
Racemization of two proteins over our lifespan: deamidation of asparagine 76 in γS crystallin is greater in cataract than in normal lenses across the age range.
PURPOSE Long-lived proteins are widespread in man, yet little is known about the processes that affect their function over time… (More)
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Review
2010
Review
2010
The role of protein L-isoaspartyl/D-aspartyl O-methyltransferase (PIMT) in intracellular signal transduction.
Under physiological conditions, L-aspartyl (L-Asp) and L-asparaginyl residues in proteins are spontaneously isomerized or… (More)
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2005
2005
Hydroxytyrosol, a natural antioxidant from olive oil, prevents protein damage induced by long-wave ultraviolet radiation in melanoma cells.
Previous studies showed that long-wave ultraviolet (UVA) radiation induces severe skin damage through the generation of reactive… (More)
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2003
2003
Quantification of the isomerization of Asp residue in recombinant human alpha A-crystallin by reversed-phase HPLC.
A method for determining the isomerization of Asp residues in proteins is described and demonstrated by quantifying the… (More)
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2000
2000
Analysis of isoaspartate in peptides by electrospray tandem mass spectrometry.
In view of the significance of Asn deamidation and Asp isomerization to isoAsp at certain sites for protein aging and turnover… (More)
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1996
1996
Synthesis of stereoisomers and isoforms of a tryptic heptapeptide fragment of human growth hormone and analysis by reverse-phase HPLC and capillary electrophoresis.
The amino acid sequence Asn-Gly has at pH 7 a tendency to induce deamidation of asparagine to aspartic acid via the formation of… (More)
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