valyl-tyrosyl-prolyl-isoaspartyl-glycyl-alanine

Deamidation is a spontaneous degenerative protein modification (DPM) that disrupts the structure and function of both endogenous… Expand

A common modification of human long-lived proteins is spontaneous isomerisation of aspartate residues, and its biological… Expand

The Asp and isoAsp isomers of three bioactive peptides, Crinia angiotensin 11 [APGDRIYHPF(OH)], uperin 1.1 [pEADPNAFYGLM(NH(2… Expand

PURPOSE Long-lived proteins are widespread in man, yet little is known about the processes that affect their function over time… Expand

Previous studies showed that long-wave ultraviolet (UVA) radiation induces severe skin damage through the generation of reactive… Expand

Deamidation of Asn residues is a major chemical pathway of degradation of peptides and proteins. To understand better the… Expand

A method for determining the isomerization of Asp residues in proteins is described and demonstrated by quantifying the… Expand

Formation of isoaspartyl peptide bonds (isoAsp) is one of the most common forms of non-enzymatic degradation of peptides and… Expand

In view of the significance of Asn deamidation and Asp isomerization to isoAsp at certain sites for protein aging and turnover… Expand

The amino acid sequence Asn-Gly has at pH 7 a tendency to induce deamidation of asparagine to aspartic acid via the formation of… Expand