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valproic acid glucuronide

Known as: VPAG 
National Institutes of Health

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Broader (1)

Valproic Acid
analogs & derivatives

Papers overview

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Highly Cited
2016
Highly Cited
2016
Neural Correlates of Fear in the Periaqueductal Gray
The dorsal and ventral periaqueductal gray (dPAG and vPAG, respectively) are embedded in distinct survival networks that… 
Review
2013
Review
2013
Efficacy and Safety of Medicinal Plants or Related Natural Products for Fibromyalgia: A Systematic Review
To assess the effects of medicinal plants (MPs) or related natural products (RNPs) on fibromyalgia (FM) patients, we evaluate the… 
2012
2012
Periaqueductal gray matter modulates the hypercapnic ventilatory response
The periaqueductal gray (PAG) is a midbrain structure directly involved in the modulation of defensive behaviors. It has direct… 
2010
2010
Identification of Valproic Acid Glucuronide Hydrolase As a Key Enzyme for the Interaction of Valproic Acid with Carbapenem Antibiotics
Plasma levels of valproic acid (VPA) are decreased by concomitant use with carbapenem antibiotics, such as panipenem (PAPM). One… 
Highly Cited
2009
Highly Cited
2009
Effect of Aging on Glucuronidation of Valproic Acid in Human Liver Microsomes and the Role of UDP-Glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10
Valproic acid (VPA) is a widely used anticonvulsant that is also approved for mood disorders, bipolar depression, and migraine… 
2009
2009
Genesis and emplacement of felsic Variscan plutons within a deep crustal lineation, the Penacova-Régua-Verín fault: An integrated geophysics and geochemical study (NW Iberian Peninsula)
2008
2008
Differential responses to morphine-induced analgesia in the tail-flick test
2004
2004
Behavioral and electrophysiological evidence for tolerance to continuous morphine administration into the ventrolateral periaqueductal gray
Highly Cited
2003
Highly Cited
2003
Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM.
It is well established that the vanilloid receptor, VR1, is an important peripheral mediator of nociception. VR1 receptors are… 
1994
1994
Antinociceptive effects of carbachol microinjected into different portions of the mesencephalic periaqueductal gray matter of the rat
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