Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

valproic acid glucuronide

Known as: VPAG 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Valproic Acid
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Neural Correlates of Fear in the Periaqueductal Gray
The dorsal and ventral periaqueductal gray (dPAG and vPAG, respectively) are embedded in distinct survival networks that… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
2012
2012
Periaqueductal gray matter modulates the hypercapnic ventilatory response
The periaqueductal gray (PAG) is a midbrain structure directly involved in the modulation of defensive behaviors. It has direct… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
2010
2010
Identification of Valproic Acid Glucuronide Hydrolase As a Key Enzyme for the Interaction of Valproic Acid with Carbapenem Antibiotics
Plasma levels of valproic acid (VPA) are decreased by concomitant use with carbapenem antibiotics, such as panipenem (PAPM). One… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Highly Cited
2009
Highly Cited
2009
Effect of Aging on Glucuronidation of Valproic Acid in Human Liver Microsomes and the Role of UDP-Glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10
Valproic acid (VPA) is a widely used anticonvulsant that is also approved for mood disorders, bipolar depression, and migraine… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
2009
2009
Genesis and emplacement of felsic Variscan plutons within a deep crustal lineation, the Penacova-Régua-Verín fault: An integrated geophysics and geochemical study (NW Iberian Peninsula)
Abstract Multidisciplinary studies integrating, U–Pb geochronology, whole-rock geochemical data, isotope geochemistry, anisotropy… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 2
2008
2008
Differential responses to morphine-induced analgesia in the tail-flick test
We compared acute and chronic antinociceptive effects of morphine in animals with high reactivity (HR) vs. low reactivity (LR) to… Expand
2004
2004
Behavioral and electrophysiological evidence for tolerance to continuous morphine administration into the ventrolateral periaqueductal gray
Repeated microinjections of morphine into the ventrolateral periaqueductal gray (vPAG) produce tolerance to the antinociceptive… Expand
Highly Cited
2003
Highly Cited
2003
Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM.
It is well established that the vanilloid receptor, VR1, is an important peripheral mediator of nociception. VR1 receptors are… Expand
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
2002
2002
Inhibition of tubulin assembly and covalent binding to microtubular protein by valproic acid glucuronide in vitro.
Acyl glucuronides are reactive metabolites of carboxylate drugs, able to undergo a number of reactions in vitro and in vivo… Expand
1994
1994
Antinociceptive effects of carbachol microinjected into different portions of the mesencephalic periaqueductal gray matter of the rat
The changes in tail-flick latency (TFL) to noxious heating of the skin produced by the microinjection of carbachol (CCh) into the… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE