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uroporphyrinogen decarboxylase activity

Known as: uroporphyrinogen-III carboxy-lyase (coproporphyrinogen-III-forming), porphyrinogen decarboxylase activity, uroporphyrinogen-III carboxy-lyase activity 
Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2. [EC:4.1.1.37]
National Institutes of Health

Papers overview

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2001
2001
Uroporphyrinogen decarboxylase (UROD) catalyzes decarboxylation of the four acetate side chains of urophyrinogen to form… Expand
1990
1990
It was previously shown that uroporphyrinogen oxidation is catalysed by a form of cytochrome P-450 induced by 3… Expand
1984
1984
Marked inhibition of porphyrinogen carboxylyase was produced in vitro by cytosol fractions, deproteinized and free of porphyrins… Expand
Highly Cited
1984
Highly Cited
1984
Abstract Hepatic iron overload amplifies the uroporphyrinogen decarboxylase enzyme defect in human porphyria cutanea tarda. To… Expand
1984
1984
The isolation of a new mutant Sm1 strain of yeast, Saccharomyces cerevisiae, is described: this strain was partially defective in… Expand
Highly Cited
1982
Highly Cited
1982
To test whether reduced hepatic uroporphyrinogen decarboxylase activity is a specific and intrinsic defect in porphyria cutanea… Expand
Highly Cited
1980
Highly Cited
1980
1. Erythrocyte uroporphyrinogen decarboxylase activity has been measured in 27 patients with porphyria cutanea tarda, of whom 11… Expand
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Highly Cited
1978
Highly Cited
1978
To test the diagnostic specificity of reduced red-cell uroporphyrinogen decarboxylase activity for porphyria cutanea tarda, we… Expand
Highly Cited
1976
Highly Cited
1976
Uroporphyrinogen decarboxylase activity was measured in liver and erythrocytes of normal subjects and in patients with porphyria… Expand
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1970
1970
Summary. Experimental hepatic siderosis in the rat due to dietary iron overload produced increased urinary excretion of uro‐ and… Expand