uroporphyrinogen-III synthase activity

Known as: uroporphyrinogen-III cosynthetase activity, porphobilinogenase activity, uroporphyrinogen isomerase activity 
Catalysis of the reaction: hydroxymethylbilane = H(2)O + uroporphyrinogen III. [EC:4.2.1.75, RHEA:18968]

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1971-2010
01219712010

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2010
2010
Splicing mutations account for approximately 10% of lesions causing genetic diseases, but few branchpoint sequence (BPS) lesions… (More)
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2010
2010
The first feline model of human congenital erythropoietic porphyria (CEP) due to deficient uroporphyrinogen III synthase (URO… (More)
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2006
2006
Congenital erythropoietic porphyria (CEP), an autosomal recessive inborn error, results from the deficient but not absent… (More)
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2006
2006
The porphyrias are heterogeneous disorders arising from predominantly inherited catalytic deficiencies of specific enzymes along… (More)
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2002
2002
The in vivo effect of the known herbicide, paraquat, on both hepatic oxidative stress and heme metabolism was studied. A marked… (More)
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2000
2000
BACKGROUND AND AIMS Acetaminophen (APAP) or paracetamol is a hepatotoxic drug through mechanisms involving oxidative stress. To… (More)
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1987
1987
Properties of Porphobilinogenase (PBGase), the enzyme complex converting porphobilinogen (PBG) into uroporphyrinogens, were… (More)
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1979
1979
A new type of haem-deficient mutant was isolated in Escherichia coli K12 by neomycin selection. The mutant was deficient in… (More)
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1976
1976
A new type of heme-deficient mutant of Salmonella typhimurium LT2 was isolated using neomycin. The mutant, designated as strain… (More)
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1971
1971
1. Porphobilinogenase was isolated and purified from soya-bean callus tissue; its components, porphobilinogen deaminase and… (More)
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