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urate catabolic process

Known as: uric acid catabolic process, urate breakdown, urate degradation 
The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine. [ISBN:0198506732]
National Institutes of Health

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2015
2015
The identification of an integral membrane, cytochrome c urate oxidase completes the catalytic repertoire of a therapeutic enzyme
In living organisms, the conversion of urate into allantoin requires three consecutive enzymes. The pathway was lost in hominid… Expand
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2012
2012
Microbial urate catabolism: characterization of HpyO, a non-homologous isofunctional isoform of the flavoprotein urate hydroxylase HpxO.
In aerobic cells, urate is oxidized to 5-hydroxyisourate by two distinct enzymes: a coenzyme-independent urate oxidase (EC 1.7.3… Expand
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2011
2011
Absolute stereochemistry and preferred conformations of urate degradation intermediates from computed and experimental circular dichroism spectra.
The enzymatic oxidation of urate leads to the sequential formation of optically active intermediates with unknown stereochemistry… Expand
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2010
2010
Urate-responsive MarR homologs from Burkholderia.
  • Anne Grove
  • Molecular bioSystems
  • 2010
    • Corpus ID: 26053681
The genus Burkholderia includes a large number of species, some of which are serious human pathogens. A genomic locus is… Expand
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2007
2007
The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.
The complete degradation of uric acid to (S)-allantoin, as recently elucidated, involves three enzymatic reactions. Inactivation… Expand
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2001
2001
Flavonoids and urate antioxidant interplay in plasma oxidative stress
Flavonoids are naturally occurring plant compounds with antioxidant properties. Their consumption has been associated with the… Expand
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1987
1987
Peroxisomal localization and activation by bivalent metal ions of ureidoglycolate lyase, the enzyme involved in urate degradation in Candida tropicalis.
Ureiodoglycolate lyase (EC 4.3.2.3) was found only in the peroxisomes in urate-induced Candida tropicalis. The enzyme was… Expand
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1986
1986
Ureidoglycollate lyase, a new metalloenzyme of peroxisomal urate degradation in marine fish liver.
Ureidoglycollate lyase (UGL, EC 4.3.2.3), which catalyses the degradation of S(-)-ureidoglycollate to urea and glyoxylate, was… Expand
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1986
1986
Evolution of allantoinase and allantoicase involved in urate degradation in liver peroxisomes. A rapid purification of amphibian allantoinase and allantoicase complex, its subunit locations of the…
Allantoinase and allantoicase are located in the same protein molecule in amphibian liver, whereas the two enzymes are different… Expand
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1981
1981
Control by phytochrome of urate oxidase and allantoinase activities during peroxisome development in the cotyledons of mustard (Sinapis alba L.) seedlings
The peroxisomal enzyme, urate oxidase (EC 1.7.3.3), and the next enzyme of the urate pathway, allantoinase (EC 3.5.2.5… Expand
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