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urate catabolic process
Known as:
uric acid catabolic process
, urate breakdown
, urate degradation
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The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine. [ISBN:0198506732]
National Institutes of Health
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2018
2018
The mycobiota of the sand fly Phlebotomus perniciosus: Involvement of yeast symbionts in uric acid metabolism
E. Martin
,
Ilaria Varotto Boccazzi
,
+8 authors
S. Epis
Environmental Microbiology
2018
Corpus ID: 4311334
The knowledge of the fungal mycobiota of arthropods, including the vectors of human and animal diseases, is still limited. Here…
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2015
2015
The identification of an integral membrane, cytochrome c urate oxidase completes the catalytic repertoire of a therapeutic enzyme
N. Doniselli
,
Enrico Monzeglio
,
A. Dal Palù
,
A. Merli
,
R. Percudani
Scientific Reports
2015
Corpus ID: 15426959
In living organisms, the conversion of urate into allantoin requires three consecutive enzymes. The pathway was lost in hominid…
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2012
2012
Microbial urate catabolism: characterization of HpyO, a non-homologous isofunctional isoform of the flavoprotein urate hydroxylase HpxO.
M. Michiel
,
Nadia Perchat
,
+6 authors
Cécile Fischer
Environmental Microbiology Reports
2012
Corpus ID: 24784623
In aerobic cells, urate is oxidized to 5-hydroxyisourate by two distinct enzymes: a coenzyme-independent urate oxidase (EC 1.7.3…
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2010
2010
Urate-responsive MarR homologs from Burkholderia.
A. Grove
Molecular Biosystems
2010
Corpus ID: 26053681
The genus Burkholderia includes a large number of species, some of which are serious human pathogens. A genomic locus is…
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2007
2007
The Structure of 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline Decarboxylase Provides Insights into the Mechanism of Uric Acid Degradation*
L. Cendron
,
R. Berni
,
C. Folli
,
Ileana Ramazzina
,
R. Percudani
,
G. Zanotti
Journal of Biological Chemistry
2007
Corpus ID: 25181613
The complete degradation of uric acid to (S)-allantoin, as recently elucidated, involves three enzymatic reactions. Inactivation…
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2004
2004
Control by phytochrome of urate oxidase and allantoinase activities during peroxisome development in the cotyledons of mustard (Sinapis alba L.) seedlings
Y. Hong
,
P. Schopfer
Planta
2004
Corpus ID: 12691607
The peroxisomal enzyme, urate oxidase (EC 1.7.3.3), and the next enzyme of the urate pathway, allantoinase (EC 3.5.2.5…
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Review
2002
Review
2002
The Physiology of Endothelial Xanthine Oxidase: From Urate Catabolism to Reperfusion Injury to Inflammatory Signal Transduction
A. Meneshian
,
G. Bulkley
Microcirculation
2002
Corpus ID: 40739497
Xanthine oxidoreductase (XOR) is a ubiquitous metalloflavoprotein that appears in two interconvertible yet functionally distinct…
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Highly Cited
2001
Highly Cited
2001
Flavonoids and urate antioxidant interplay in plasma oxidative stress
P. Filipe
,
V. Lança
,
João Nuno Silva
,
P. Morlière
,
R. Santus
,
A. Fernandes
Molecular and Cellular Biochemistry
2001
Corpus ID: 6179708
Flavonoids are naturally occurring plant compounds with antioxidant properties. Their consumption has been associated with the…
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1986
1986
Evolution of allantoinase and allantoicase involved in urate degradation in liver peroxisomes. A rapid purification of amphibian allantoinase and allantoicase complex, its subunit locations of the…
T. Noguchi
,
S. Fujiwara
,
S. Hayashi
Journal of Biological Chemistry
1986
Corpus ID: 39983636
Allantoinase and allantoicase are located in the same protein molecule in amphibian liver, whereas the two enzymes are different…
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1986
1986
Ureidoglycollate lyase, a new metalloenzyme of peroxisomal urate degradation in marine fish liver.
Y. Takada
,
T. Noguchi
Biochemical Journal
1986
Corpus ID: 12917873
Ureidoglycollate lyase (UGL, EC 4.3.2.3), which catalyses the degradation of S(-)-ureidoglycollate to urea and glyoxylate, was…
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