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ubiquitin protein ligase binding

Known as: ubiquitin ligase binding 
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins. [GOC:vp]
National Institutes of Health

Papers overview

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2019
2019
ERK-dependent proteasome degradation of Txnip regulates thioredoxin oxidoreductase activity
Dynamic control of thioredoxin (Trx) oxidoreductase activity is essential for balancing the need of cells to rapidly respond to… Expand
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Review
2019
Review
2019
Control Mechanisms of the Tumor Suppressor PDCD4: Expression and Functions
PDCD4 is a novel tumor suppressor to show multi-functions inhibiting cell growth, tumor invasion, metastasis, and inducing… Expand
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2017
2017
Proteolytic degradation of regulator of G protein signaling 2 facilitates temporal regulation of Gq/11 signaling and vascular contraction
Regulator of G protein signaling 2 (RGS2) controls signaling by receptors coupled to the Gq/11 class heterotrimeric G proteins… Expand
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2015
2015
Abstract 4679: Silencing of PMEPA1, a NEDD4 E3 ubiquitin ligase binding protein, stabilizes androgen receptor and confers resistance to AR inhibitors
 
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2015
2015
Silencing of PMEPA1 accelerates the growth of prostate cancer cells through AR, NEDD4 and PTEN
Androgen Receptor (AR) is the male hormone receptor and a nuclear transcription factor which plays a central role in the growth… Expand
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2015
2015
Rational design of a photo-crosslinking BODIPY for in situ protein labeling.
Photo-crosslinking agents have emerged as critical tools to investigate protein-protein interactions in complex proteomes, but… Expand
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2011
2011
Thioredoxin Regulates Adipogenesis through Thioredoxin-interacting Protein (Txnip) Protein Stability*♦
Txnip (thioredoxin-interacting protein) is a critical mediator of metabolism and adipogenesis in vivo. The mechanisms of action… Expand
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Highly Cited
2008
Highly Cited
2008
APC is essential for targeting phosphorylated beta-catenin to the SCFbeta-TrCP ubiquitin ligase.
Ubiquitin-dependent proteolysis is an important mechanism that suppresses the beta-catenin transcription factor in cells without… Expand
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2005
2005
The N-end rule ubiquitin-conjugating enzyme, HR6B, is up-regulated by nerve growth factor and required for neurite outgrowth
Neurite outgrowth is accompanied by increased levels of high molecular weight ubiquitin conjugates and decreased levels of free… Expand
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2001
2001
Processing of p105 Is Inhibited by Docking of p50 Active Subunits to the Ankyrin Repeat Domain, and Inhibition Is Alleviated by Signaling via the Carboxyl-terminal Phosphorylation/ Ubiquitin-Ligase…
Processing of the p105 precursor to generate the p50 subunit of the nuclear factor κB transcription factor is an exceptional case… Expand
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