ubiquitin-dependent protein catabolic process

Known as: ubiquitin-dependent proteolysis, ubiquitin-dependent protein catabolism, ubiquitin-dependent protein degradation 
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent… (More)
National Institutes of Health

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2012
2012
Skeletal muscle atrophy is a consequence of muscle inactivity resulting from denervation, unloading and immobility. It… (More)
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Highly Cited
2007
Highly Cited
2007
Notch signaling is of crucial importance in normal T-cell development and Notch 1 is frequently mutated in T-cell acute… (More)
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2005
2005
Ubiquitin plays essential roles in various cellular processes; therefore, it is of keen interest to study the structure-function… (More)
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Highly Cited
2004
Highly Cited
2004
Muscle wasting accompanies aging and pathological conditions ranging from cancer, cachexia, and diabetes to denervation and… (More)
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2003
2003
Effects of glutamine on whole body and intestinal protein synthesis and on intestinal proteolysis were assessed in humans. Two… (More)
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Highly Cited
2000
Highly Cited
2000
The c-Myc oncoprotein plays an important role in the growth and proliferation of normal and neoplastic cells. To execute these… (More)
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Highly Cited
1998
Highly Cited
1998
Upon activation in response to cellular stress or DNA damage, the p53 tumor suppressor induces the expression of gene products… (More)
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Highly Cited
1996
Highly Cited
1996
Recent studies suggest that sepsis-induced increase in muscle proteolysis mainly reflects energy-ubiquitin-dependent protein… (More)
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1995
1995
A variety of protease inhibitors have been used to study ubiquitin-dependent proteolysis by the 26 S protease. However, these… (More)
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Highly Cited
1994
Highly Cited
1994
To obtain information on the role of proteasomes in the immune system, we examined the effect of a major immunomodulatory… (More)
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