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tyrphostin AG957

Known as: AG957, Tyrphostin AG 957, AG 957 
A member of the tyrphostin family of tyrosine kinase inhibitors that selectively inhibits human p210 tyrosine kinase activity. (NCI)
National Institutes of Health

Papers overview

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2003
2003
The present study investigated the effects of protein tyrosine kinase inhibitors on the fast sodium current (INa) in rabbit… 
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2002
2002
AG957 (NSC 654705) is a tyrphostin tyrosine kinase inhibitor that has been demonstrated previously to induce growth arrest in… 
2002
2002
Abstract Purpose.NSC 680410, the novel adamantyl ester of AG957, an inhibitor of the p210bcr/abl tyrosine kinase (CML, Ph+) and… 
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Review
2001
Review
2001
Clinical circumvention of multidrug resistance (MDR) is a Sisyphian task faced in the treatment of many cancers. Identification… 
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Highly Cited
2001
Highly Cited
2001
STI571 (formerly CGP57148) and AG957 are small molecule inhibitors of the protein tyrosine kinase (PTK) p145(abl) and its… 
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Highly Cited
2000
Highly Cited
2000
The tyrphostin AG957 (NSC 654705) inhibits p210bcr/abl, the transforming kinase responsible for most cases of chronic myelogenous… 
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1999
1999
The hallmark of chronic myelogenous leukemia (CML) is the Philadelphia (Ph) chromosome that fuses genetic sequences of the BCR… 
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1998
1998
Abnormal β1 integrin receptor function may contribute to the continuous proliferation and abnormal circulation of malignant… 
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1996
1996
AG957 is a tyrosine kinase antagonist which prior studies had shown inhibits p2106bcr abl tyrosine kinase activity and K562… 
Highly Cited
1994
Highly Cited
1994
We have examined a series of tyrosine kinase inhibitors structurally related to erbstatin (tyrphostins) for inhibition of p210bcr…