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tyrphostin AG957

Known as: AG957, Tyrphostin AG 957, AG 957 
A member of the tyrphostin family of tyrosine kinase inhibitors that selectively inhibits human p210 tyrosine kinase activity. (NCI)
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Benzylidene CompoundsNitrilesTyrphostins
Receptor Tyrosine Kinase Inhibition

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
The LAR protein tyrosine phosphatase enables PDGF β-receptor activation through attenuation of the c-Abl kinase activity.
2006
2006
Molecular Mechanism of Adaphostin-mediated G1 Arrest in Prostate Cancer (PC-3) Cells
Adaphostin (NSC680410), a small molecule congener of tyrphostin AG957, has been demonstrated previously to have significant anti… 
2005
2005
The tyrosine kinase inhibitors imatinib and AG957 reverse multidrug resistance in a chronic myelogenous leukemia cell line.
2005
2005
Metabolic alterations in K562 cells exposed to taxol and tyrphostin AG957: 1H NMR and biochemical studies
2003
2003
Inhibition of fast sodium current in rabbit ventricular myocytes by protein tyrosine kinase inhibitors
The present study investigated the effects of protein tyrosine kinase inhibitors on the fast sodium current (INa) in rabbit… 
2003
2003
Two-step formation of 1H NMR visible mobile lipids during apoptosis of paclitaxel-treated K562 cells.
2002
2002
Regulation of Transient Outward Current in Human Atrial Myocytes by Protein Tyrosine Kinase Pathway
Regulation of Transient Outward Current. Introduction: Regulation of transient outward current (Ito) in human myocytes is unclear… 
2002
2002
Mechanisms of apoptosis by the tyrphostin AG957 in hematopoietic cells.
1996
1996
Altered physical state of p21bcr—abl in tyrphostin AG957-treated K562 cells
AG957 is a tyrosine kinase antagonist which prior studies had shown inhibits p2106bcr abl tyrosine kinase activity and K562… 
Highly Cited
1994
Highly Cited
1994
Tyrphostin induced growth inhibition: correlation with effect on p210bcr-abl autokinase activity in K562 chronic myelogenous leukemia.
We have examined a series of tyrosine kinase inhibitors structurally related to erbstatin (tyrphostins) for inhibition of p210bcr… 
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