tyrphostin A23

Known as: 3,4-dihydroxybenzylidenemalononitrile, 18 aged, (3,4-dihydroxybenzylidene)malononitrile 
A broad spectrum protein tyrosine kinase inhibitor that inhibits epidermal growth factor receptor, GTPase activity of transducin, aldosterone… (More)
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
The objective of the present study was to investigate the effect of leptin, alone or in combination with IL-1, on nitric oxide… (More)
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Highly Cited
2004
Highly Cited
2004
The mechanisms underlying caspase-1 activation and IL-1beta processing during inflammatory activation of monocytes and… (More)
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Highly Cited
2003
Highly Cited
2003
Several intracellular membrane trafficking events are mediated by tyrosine-containing motifs within the cytosolic domains of… (More)
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Highly Cited
2002
Highly Cited
2002
Cannabinoids, the active components of marijuana and their endogenous counterparts, exert many of their actions in brain through… (More)
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Highly Cited
2002
Highly Cited
2002
OBJECTIVES Ghrelin is a brain-gut peptide with GH-releasing and appetite-inducing activities and a widespread tissue distribution… (More)
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Highly Cited
2000
Highly Cited
2000
The receptor for insulin-like growth factor 1 (IGF-1) mediates multiple cellular responses, including stimulation of both… (More)
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Highly Cited
2000
Highly Cited
2000
Overexpression of interleukin 6, a downstream target of the GBX2 homeobox gene, has been linked to the progression of prostate… (More)
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Highly Cited
1999
Highly Cited
1999
G protein-coupled receptors (GPCRs) initiate Ras-dependent activation of the Erk 1/2 mitogen-activated protein kinase cascade by… (More)
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Highly Cited
1998
Highly Cited
1998
Adhesion of human primary skin fibroblasts and ECV304 endothelial cells to immobilized matrix proteins, beta1 or alphav integrin… (More)
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Highly Cited
1997
Highly Cited
1997
Mycosis fungoides (MF) is a low-grade cutaneous T cell lymphoma of unknown etiology. In this report, the Jak/Stat (Janus kinase… (More)
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