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tylophorine

Known as: (S)-9,11,12,13,13a,14-hexahydro-2,3,6,7- tetramethoxydibenzo(f,h)pyrrolo(1,2-b)isoquinoline, 2,3,6,7-tetramethoxyphenanthro(9,10:6,7')indolizidine 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

AlkaloidsIndolizinesPhenanthrenes
dehydrotylophorine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Tylophorine Analogs Allosterically Regulates Heat Shock Cognate Protein 70 And Inhibits Hepatitis C Virus Replication
Tylophorine analogs have been shown to exhibit diverse activities against cancer, inflammation, arthritis, and lupus in vivo. In… 
2012
2012
Hepatitis C virus non-structural 5B protein interacts with cyclin A2 and regulates viral propagation.
2011
2011
Extraction of tylophorine from in vitro raised plants of Tylophora indica
A method for mass propagation of Tylophora indica (Burm. f.) Merill. (Asclepiadaceae) from leaf explants and extraction of… 
2009
2009
A concise palladium-catalyzed carboamination route to (+/-)-tylophorine.
A total synthesis of the racemic natural product tylophorine [(+/-)-1] has been demonstrated using the palladium-catalyzed… 
2009
2009
Synthesis of (S)-(+)-tylophorine and its seco analogues using free radical reaction
The synthesis of (S)-(+)-tylophorine and its seco analogues has been accomplished by using free radical reaction. (−)-N-(2,3,6,7… 
Highly Cited
2008
Highly Cited
2008
A general approach to triphenylenes and azatriphenylenes: total synthesis of dehydrotylophorine and tylophorine.
A convergent and flexible synthesis of substituted triphenylenes, azatriphenylenes, and the cytotoxic alkaloids… 
Highly Cited
2006
Highly Cited
2006
Inhibition of cell growth and nuclear factor-κB activity in pancreatic cancer cell lines by a tylophorine analogue, DCB-3503
A tylophorine analogue, DCB-3503, has been shown to have potent activity against tumor growth in vitro and in vivo, as well as… 
Highly Cited
1979
Highly Cited
1979
Pharmacological investigations of tylophorine, the major alkaloid of Tylophora indica.
1971
1971
Alkaloids of tylophora. 3. New alkaloids of Tylophora indica (Burm) Merrill and Tylophora dalzellii Hook. f.
During a reexamination of the alkaloidal constituents of Tylophora indica, three new alkaloids (designated A, B, and C) were… 
Highly Cited
1970
Highly Cited
1970
Common receptor-complement feature among some antileukemic compounds.
A common structural feature was found among some nonalkylating antileukemic agents such as aminopterin, anthramycin, 5… 
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