trypsinogen activation

Known as: cleavage of trypsinogen to trypsin 
The proteolytic processing of trypsinogen to the active form, trypsin. [GOC:mah]
National Institutes of Health

Papers overview

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2014
2014
The pathogenesis of chronic pancreatitis (CP) is poorly understood. Endoplasmic reticulum (ER) stress has now been recognized as… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND & AIMS The role of trypsinogen activation in the pathogenesis of acute pancreatitis (AP) has not been clearly… (More)
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2011
2011
Alcohol abuse is a major global health problem, but there is still much uncertainty about the mechanisms of action. So far, the… (More)
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2006
2006
Trypsin-mediated trypsinogen activation (autoactivation) facilitates digestive zymogen activation in the duodenum but may… (More)
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2003
2003
The activation peptide of mammalian trypsinogens contains a highly conserved tetra-aspartate sequence (D19-D20-D21-D22) preceding… (More)
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2002
2002
BACKGROUND & AIMS Prior thermal stress induces heat shock protein 70 (HSP70) expression in the pancreas and protects against… (More)
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2001
2001
Intra-acinar cell nuclear factor-kappaB (NF-kappaB) and trypsinogen activation are early events in secretagogue-induced acute… (More)
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2001
2001
Hyperthermia, raising the body temperature from normal to above 40 degrees C, has been shown to prevent pancreatitis in an… (More)
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2000
2000
Rodents given a supramaximally stimulating dose of cholecystokinin or its analogue cerulein develop acute pancreatitis with… (More)
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1996
1996
Ligation of the common bile-pancreatic duct induces hyperamylasemia and acute pancreatitis in rats. Pancreatic morphologic… (More)
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