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trospium chloride

Known as: azoniaspiro compound XVII, azoniaspiro(3 alpha-benziloyloxynortropane-8,1'- pyrrolidine) chloride 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (5)

BenzilatesMuscarinic AntagonistsNortropanesParasympatholytics

Narrower (5)

CerisSancturaSpasmexSpasmo-Urgenin
Trospium

Papers overview

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2009
2009
The Role of P-Glycoprotein in Limiting Brain Penetration of the Peripherally Acting Anticholinergic Overactive Bladder Drug Trospium Chloride
The aim of the present study was to characterize the role of the drug-efflux transporter P-glycoprotein (P-gp) for the… 
2008
2008
Water balance in a poorly gauged basin in West Africa using atmospheric modelling and remote sensing information
Sustainable water resources management under increasing water demands and changing climate conditions is a central, socio… 
2004
2004
Effect of trospium chloride on somnolence and sleepiness in patients with overactive bladder
An objective of a large US phase-3 study was to determine the effects of trospium chloride 20-mg tablets versus placebo… 
2004
2004
Absorption pattern of trospium chloride along the human gastrointestinal tract assessed using local enteral administration.
BACKGROUND AND OBJECTIVES The antimuscarinic drug trospium chloride is hydrophilic and therefore does not enter the CNS when used… 
Review
2001
Review
2001
Trospium chloride – an effective drug in the treatment of overactive bladder and detrusor hyperreflexia
Abstract Trospium chloride (TCL), a quaternary ammonium derivative of nortropanol, has been evaluated in a number of clinical and… 
Highly Cited
2000
Highly Cited
2000
Efficacy of trospium chloride in patients with detrusor instability: a placebo‐controlled, randomized, double‐blind, multicentre clinical trial
Objectives To assess the efficacy and safety of trospium chloride (TCl, 20 mg twice daily) in the treatment of detrusor… 
1999
1999
Inhibitory effects of trospium chloride on cytochrome P450 enzymes in human liver microsomes.
Trospium chloride, an atropine derivative used for the treatment of urge incontinence, was tested for inhibitory effects on human… 
1991
1991
[High-dose trospium chloride in therapy of detrusor hyperreflexia].
The efficacy and tolerance of a high-dose treatment with trospium chloride (20 mg twice daily) were investigated in pilot studies… 
1986
1986
Determination of the bioavailability of the quaternary compound trospium chloride in man from urinary excretion data.
For the quaternary compound trospium chloride (Spasmex) which is used as an anticholinergic agent a new sensitive assay method… 
1980
1980
Élisabeth Badinter, L'Amour en plus : histoire de l'amour maternel (XVII-XXe siècle), Paris, Flammarion, 1980
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