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troglitazone sulfate

Known as: TGZS cpd 
National Institutes of Health

Papers overview

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2017
2017
The interference of bile acid secretion through bile salt export pump (BSEP) inhibition is one of the mechanisms for troglitazone… Expand
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2015
2015
The bile salt export pump (BSEP) plays an important role in bile acid excretion. Impaired BSEP function may result in liver… Expand
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Highly Cited
2010
Highly Cited
2010
This study examined the hepatobiliary disposition of troglitazone (TGZ) and metabolites [TGZ sulfate (TS), TGZ glucuronide (TG… Expand
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Highly Cited
2007
Highly Cited
2007
Hepatic uptake carriers of the organic anion-transporting peptide (OATP) family of solute carriers are more and more recognized… Expand
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2007
2007
Troglitazone sulfate (TGZS) is the major metabolite of troglitazone (TGZ), an antidiabetic agent, and thought to be a cause of… Expand
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Highly Cited
2004
Highly Cited
2004
Troglitazone is a thiazolidinedione insulin sensitizer drug that is metabolized mainly to a sulfate conjugate (M-1) in humans. It… Expand
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Highly Cited
2001
Highly Cited
2001
Troglitazone is a thiazolidinedione insulin sensitizer drug for the treatment of type 2 non-insulin-dependent diabetes mellitus… Expand
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Highly Cited
2001
Highly Cited
2001
We investigated whether lack of the canalicular multispecific organic anion transporter in transport-deficient (TR-) rats would… Expand
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Highly Cited
2000
Highly Cited
2000
In primary human and porcine hepatocyte cultures, we investigated the relationship between metabolism and cytotoxicity of… Expand
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1998
1998
Troglitazone, a PPAR-gamma agonist, enhances the actions of insulin on muscle and liver. It is metabolized predominantly in the… Expand