triphenylmethylphosphonium

Mitochondria-targeted molecules comprising the lipophilic TPP (triphenylphosphonium) cation covalently linked to a hydrophobic… (More)

Lipophilic monocations can pass through phospholipid bilayers and accumulate in negatively-charged compartments such as the… (More)

Cytochrome c release from mitochondria is central to apoptosis, but the events leading up to it are disputed. The mitochondrial… (More)

Multidrug transport system in proteoliposomes was reconstituted using the highly purified membrane transport protein responsible… (More)

Bloodstream forms of Trypanosoma brucei were found to maintain a significant membrane potential across their mitochondrial inner… (More)

A technique for the rapid production of large unilamellar vesicles by repeated extrusion under moderate pressures (≤ 500 lb/in… (More)

Triphenylmethylphosphonium (TPMP) blocked the nerve-elicited twitch tension of frog sartorius muscles by 50% at a concentration… (More)

1. We have monitored the plasma-membrane potential of lymphocytes by measuring the accumulation of the lipophilic cation… (More)

A method is described, based on the differential accumulation of Rb+ and methyltriphenylphosphonium, for the simultaneous… (More)

Transmembrane electrical and pH gradients have been measured across human erythrocytes and peripheral blood lymphocytes using… (More)