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trihalobenzocycloheptapyridine

National Institutes of Health

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2 relations

Broader (1)

Pyridines
TH-BCHP

Papers overview

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1999
1999
Identification of pharmacokinetically stable 3, 10-dibromo-8-chlorobenzocycloheptapyridine farnesyl protein transferase inhibitors with potent enzyme and cellular activities.
Farnesyl protein transferase (FPT) is a promising target for the development of cancer chemotherapeutics because it is… 
1999
1999
Atropisomeric trihalobenzocycloheptapyridine analogues provide stereoselective FPT inhibitors with antitumor activity.
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