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triclabendazole sulfoxide

Known as: TCBZ-SX 
National Institutes of Health

Related topics

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2 relations

Broader (2)

BenzimidazolesSulfoxides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Effects of triclabendazole on secretion of danofloxacin and moxidectin into the milk of sheep: role of triclabendazole metabolites as inhibitors of the ruminant ABCG2 transporter.
2013
2013
Fasciola hepatica: histological demonstration of apoptosis in the reproductive organs of flukes of triclabendazole-sensitive and triclabendazole-resistant isolates, and in field-derived flukes from…
2012
2012
The Anthelmintic Triclabendazole and Its Metabolites Inhibit the Membrane Transporter ABCG2/BCRP
ABSTRACT ABCG2/BCRP is an ATP-binding cassette transporter that extrudes compounds from cells in the intestine, liver, kidney… 
Highly Cited
2010
Highly Cited
2010
Interaction of anthelmintic drugs with P-glycoprotein in recombinant LLC-PK1-mdr1a cells.
2010
2010
Enhancement of the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica using the metabolic inhibitor ketoconazole
A study has been carried out to investigate whether the action of triclabendazole (TCBZ) is altered by using the metabolic… 
2007
2007
Pharmacokinetic disposition of triclabendazole in cattle and sheep; discrimination of the order and the rate of the absorption process of its active metabolite triclabendazole sulfoxide
A comparative pharmacokinetic study was conducted to determine the order and the rate of absorption of triclabendazole (TCBZ) in… 
Highly Cited
1998
Highly Cited
1998
Effect of food on the bioavailability of triclabendazole in patients with fascioliasis.
AIMS Preliminary results indicate higher absorption of triclabendazole (TCBZ) administered postprandially. Therefore, the… 
1996
1996
Efficacy and pharmacokinetics of triclabendazole in buffalo with induced fasciolosis.
1995
1995
Kinetic disposition of triclabendazole in buffalo compared to cattle.
Concentrations of triclabendazole sulfoxide and its sulfone metabolite in plasma were measured in buffalo and cross-bred cattle… 
Highly Cited
1987
Highly Cited
1987
The kinetics of triclabendazole disposition in sheep.
To investigate whether the disposition of triclabendazole (TCBZ) and its metabolites in blood or bile influenced its flukicidal… 
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