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trequinsin

 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
5′-Fluorouracil (5-FU), used in the treatment of colon and breast cancers, is converted intracellularly to 5′-fluoro-2… Expand
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Highly Cited
2003
Highly Cited
2003
The human multidrug resistance proteins MRP4 and MRP5 are organic anion transporters that have the unusual ability to transport… Expand
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Highly Cited
2002
Highly Cited
2002
PURPOSE The intracellular messenger cyclic guanosine monophosphate (cGMP) has an important role in regulating smooth muscle tone… Expand
Highly Cited
2000
Highly Cited
2000
Cellular export of cyclic nucleotides has been observed in various tissues and may represent an elimination pathway for these… Expand
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Review
1997
Review
1997
cAMP-specific phosphodiesterase inhibitors display a range of activities in vitro and in vivo which suggest they may be useful in… Expand
Highly Cited
1992
Highly Cited
1992
Studies by various investigators have demonstrated that the low Km, cAMP-specific phosphodiesterase (PDE IV) is selectively… Expand
Highly Cited
1990
Highly Cited
1990
Experiments were carried out in order to isolate and characterize the cyclic nucleotide phosphodiesterase activities in primary… Expand
Highly Cited
1990
Highly Cited
1990
Two cyclic nucleotide phosphodiesterase (PDE) activities were identified in pig aortic endothelial cells, a cyclic GMP-stimulated… Expand
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Highly Cited
1986
Highly Cited
1986
Cyclic nucleotide phosphodiesterase (PDE) activity from the 105,000 g supernatant of human, bovine and rat aorta smooth muscle… Expand
1984
1984
Series of 3-substituted-9,10-dimethoxy-3,4,6,7-tetrahydro-2H-pyrimido [6,1-a]isoquinoline-2,4-diones and 2-substituted-9,10… Expand