trefoil factor

Known as: Trefoil Proteins, Trefoil Factor Family Peptides, Trefoil Factors [Chemical/Ingredient] 
A family of small peptides expressed primarily by MUCOUS MEMBRANE EPITHELIAL CELLS in vertebrates. Their structure is highly conserved and is defined… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
0204019772017

Papers overview

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Highly Cited
2001
Highly Cited
2001
Mucosal organs such as the intestine are supported by a rich and complex underlying vasculature. For this reason, the intestine… (More)
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Highly Cited
2000
Highly Cited
2000
Intestinal trefoil factor (ITF) is an essential regulator of colonic epithelial restitution, the rapid migration of colonocytes… (More)
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Highly Cited
1998
Highly Cited
1998
Intestinal trefoil factor 3 (TFF3) is a member of the trefoil family of peptides, small molecules constitutively expressed in… (More)
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Highly Cited
1996
Highly Cited
1996
The mechanisms that maintain the epithelial integrity of the gastrointestinal tract remain largely undefined. The gene encoding… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND & AIMS The trefoil factors, a family of proteins abundantly expressed in gastrointestinal mucous cells, protect the… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND & AIMS Goblet cells secrete a combination of trefoil peptides and mucin glycoproteins to form a continuous gel on the… (More)
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Highly Cited
1995
Highly Cited
1995
A model of gastric ulceration in the rat has been used to determine the expression of four messenger RNAs (mRNAs) encoding… (More)
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Highly Cited
1994
Highly Cited
1994
The trefoil peptides, a recently recognized family of protease-resistant peptides, expressed in a regional specific pattern… (More)
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Highly Cited
1993
Highly Cited
1993
Trefoil peptides are a recently recognized group of small peptides abundantly produced at mucosal surfaces that offer the… (More)
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Highly Cited
1991
Highly Cited
1991
The trefoil peptide family encompasses a group of small proteins that appear to assume a distinctive secondary structure that… (More)
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