translational termination

Known as: translation termination, translational complex disassembly 
The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2017
020406019752017

Papers overview

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Review
2016
Review
2016
Premature translation termination leads to a reduced mRNA level in all types of organisms. In eukaryotes, the phenomenon is known… (More)
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Highly Cited
2008
Highly Cited
2008
The termination of protein synthesis occurs through the specific recognition of a stop codon in the A site of the ribosome by a… (More)
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Highly Cited
2006
Highly Cited
2006
Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that degrades mRNA containing premature termination codons (PTCs… (More)
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Highly Cited
2000
Highly Cited
2000
Nonsense-mediated decay (NMD) rids eukaryotic cells of aberrant mRNAs containing premature termination codons. These are… (More)
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Highly Cited
2000
Highly Cited
2000
Vertebrate photoreceptor cells are the basic sensory apparatus of the retina, capable of converting the energy of absorbed… (More)
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Highly Cited
1997
Highly Cited
1997
In cellular regulatory networks, genetic activity is controlled by molecular signals that determine when and how often a given… (More)
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Highly Cited
1995
Highly Cited
1995
Vascular endothelial growth factor (VEGF), a potent angiogenic factor and endothelial cell-specific mitogen, is up-regulated by… (More)
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Highly Cited
1994
Highly Cited
1994
The degradation of messenger RNA in eukaryotic cells is initiated by endonucleolytic cleavage or by shortening of the poly(A… (More)
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Highly Cited
1991
Highly Cited
1991
mRNA decay rates often increase when translation is terminated prematurely due to a frameshift or nonsense mutation. We have… (More)
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Highly Cited
1984
Highly Cited
1984
A new method for in vitro insertional mutagenesis of genes cloned in Escherichia coli is presented. This simple procedure… (More)
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