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Mitochondrial fission and fusion are essential processes in the maintenance of the skeletal muscle function. The contribution of… Expand Stress-regulated signaling pathways protect mitochondrial proteostasis and function from pathologic insults. Despite the… Expand
Reduction of the CHOP target Gadd34 restores motor function in P0S63del mice with demyelinating neuropathy.
Clustered codons that pair to low-abundance tRNA isoacceptors can form slow-translating regions in the mRNA and cause transient… Expand Viral infection induces endoplasmic reticulum (ER) stress and interferon responses. While viral double-stranded RNA intermediates… Expand Abstract Both microRNAs (miRNA) and small interfering RNAs (siRNA) share a common set of cellular proteins (Dicer and the RNA… Expand Vitamin B1 in its active form thiamin pyrophosphate is an essential coenzyme that is synthesized by coupling of pyrimidine… Expand The unfolded protein response (UPR) is a transcriptional and translational intracellular signaling pathway activated by the… Expand The Neurospora crassa arg-2 upstream open reading frame (uORF) plays a role in negative arginine-specific translational… Expand The regulation of ermC is described in detail as an example of regulation on the level of translation. ermC specifies a ribosomal… Expand