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transferrin receptor 2, human

Known as: TfR2, Transferrin Receptor Protein 2, Transferrin Receptor 2 
Transferrin receptor protein 2 (801 aa, ~89 kDa) is encoded by the human TFR2 gene. This protein is involved in the mediation of cellular uptake of… Expand
National Institutes of Health

Papers overview

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Review
2010
Review
2010
In the late 1800s, hemochromatosis was considered an odd autoptic finding. More than a century later, it was finally recognized… Expand
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Highly Cited
2009
Highly Cited
2009
The mechanisms that allow the body to sense iron levels in order to maintain iron homeostasis are unknown. Patients with the most… Expand
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Highly Cited
2009
Highly Cited
2009
UNLABELLED Hepcidin is a central regulator of iron homeostasis. HFE and transferrin receptor 2 (TFR2) are mutated in adult-onset… Expand
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Highly Cited
2006
Highly Cited
2006
HFE and transferrin receptor 2 (TFR2) are membrane proteins integral to mammalian iron homeostasis and associated with human… Expand
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Highly Cited
2006
Highly Cited
2006
Recently, it has been suggested that hepcidin, a peptide involved in iron homeostasis, is regulated by bone morphogenetic… Expand
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Highly Cited
2004
Highly Cited
2004
Transferrin receptor 2 (TfR2) is a type 2 transmembrane protein expressed in hepatocytes that binds iron-bound transferrin (Tf… Expand
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Highly Cited
2004
Highly Cited
2004
Transferrin receptor 2 (TfR2) plays a critical role in iron homeostasis because patients carrying disabling mutations in the TFR2… Expand
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Highly Cited
2000
Highly Cited
2000
The transferrin receptor (TfR) interacts with two proteins important for iron metabolism, transferrin (Tf) and HFE, the protein… Expand
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Highly Cited
2000
Highly Cited
2000
In most cells, transferrin receptor (TfR1)-mediated endocytosis is a major pathway for cellular iron uptake. We recently cloned… Expand
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Highly Cited
1999
Highly Cited
1999
Transferrin receptor (TfR) plays a major role in cellular iron uptake through binding and internalizing a carrier protein… Expand
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