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transferrin receptor 2, human

Known as: TfR2, Transferrin Receptor Protein 2, Transferrin Receptor 2 
Transferrin receptor protein 2 (801 aa, ~89 kDa) is encoded by the human TFR2 gene. This protein is involved in the mediation of cellular uptake of… 
National Institutes of Health

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Related topics

16 relations
Cellular MembraneErythropoiesisIntegral Membrane ProteinsIonophore activity

Broader (1)

Transferrin Receptor

Papers overview

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2015
2015
Hepatocyte Nuclear Factor 4 (cid:2) Controls Iron Metabolism and Regulates Transferrin Receptor 2 in Mouse Liver *
Iron is an essential element in biological systems, but excess iron promotes the formation of reactive oxygen species, resulting… 
Review
2010
Review
2010
Advancement of the study on iron metabolism and regulation in tumor cells.
As an essential metal for sustaining life, iron is involved in a number of metabolic processes, including DNA synthesis, electron… 
2008
2008
HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron.
2007
2007
Effects of alcohol consumption on iron metabolism in mice with hemochromatosis mutations.
BACKGROUND Alcoholic liver disease is associated with increased hepatic iron accumulation. The liver-derived peptide hepcidin is… 
2007
2007
Localization of the iron-regulatory proteins hemojuvelin and transferrin receptor 2 to the basolateral membrane domain of hepatocytes
The newly discovered proteins hemojuvelin (Hjv) and transferrin receptor type 2 (TfR2) are involved in iron metabolism. Mutations… 
Review
2005
Review
2005
Advances in understanding the molecular basis for the regulation of dietary iron absorption
Purpose of review The number of newly identified genes participating in the regulation of iron homeostasis has continued to… 
2004
2004
Inactivation of the murine Transferrin Receptor 2 gene using the Cre recombinase: LoxP system
Summary: Transferrin Receptor 2 (TfR2) is a key molecule involved in the regulation of iron homeostasis. Mutations in TfR2 lead… 
2003
2003
Heterotypic interactions between transferrin receptor and transferrin receptor 2.
Cellular iron uptake in most tissues occurs via endocytosis of diferric transferrin (Tf) bound to the transferrin receptor (TfR… 
2003
2003
Molecular evidence for transferrin receptor 2 expression in all FAB subtypes of acute myeloid leukemia.
2003
2003
Effects of cell proliferation on the uptake of transferrin‐bound iron by human hepatoma cells
The effects of cellular proliferation on the uptake of transferrin‐bound iron (Tf‐Fe) and expression of transferrin receptor‐1… 
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