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trans-translation

A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation… Expand
National Institutes of Health

Papers overview

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Review
2012
Review
2012
ABSTRACT Mycobacterial persisters, the survivors from antibiotic exposure, necessitate the lengthy treatment of tuberculosis (TB… Expand
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Highly Cited
2011
Highly Cited
2011
The target of a first-line tuberculosis drug that acts against persister bacteria is identified. Pyrazinamide (PZA) is a first… Expand
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Highly Cited
2010
Highly Cited
2010
Although SsrA(tmRNA)‐mediated trans‐translation is thought to maintain the translation capacity of bacterial cells by rescuing… Expand
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Review
2008
Review
2008
  • K. Keiler
  • Annual review of microbiology
  • 2008
  • Corpus ID: 7822012
The trans-translation mechanism is a key component of multiple quality control pathways in bacteria that ensure proteins are… Expand
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Highly Cited
2005
Highly Cited
2005
SsrA is a versatile RNA molecule found in all bacteria that functions as both a tRNA and an mRNA. SsrA rescues ribosomes stalled… Expand
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Highly Cited
2003
Highly Cited
2003
An important unsolved question regarding the bacterial SsrA system is the fate of target mRNAs replaced by SsrA RNA during trans… Expand
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Highly Cited
2002
Highly Cited
2002
tmRNA has a dual function as a tRNA and an mRNA to facilitate trans-translation, in which a ribosome can switch between… Expand
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Highly Cited
2002
Highly Cited
2002
The function of SmpB protein in the trans‐translation system was evaluated using the well‐defined cell‐free translation system… Expand
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Highly Cited
2001
Highly Cited
2001
tmRNA facilitates a novel translation, trans-translation, in which a ribosome can switch between translation of a truncated mRNA… Expand
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Highly Cited
1999
Highly Cited
1999
The small, stable RNA molecule encoded by ssrA, known as tmRNA or 10Sa RNA, is required for the growth of certain hybrid… Expand
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