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trans-3'-hydroxycotinine

 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The nicotine metabolite cotinine is widely used to assess the extent of tobacco use in smokers, and secondhand smoke exposure in… Expand
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2009
2009
An LC-MS/MS method for the simultaneous quantification of nicotine, cotinine, trans-3'-hydroxycotinine and norcotinine in human… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Several studies have reported that female smokers have a higher risk of lung cancer than male smokers. This could be… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Nicotine and a variety of other drugs and toxins are metabolized by cytochrome P450 (CYP) 2A6. Our objective was to… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Assessment of nicotine metabolism and disposition has become an integral part of nicotine dependency treatment… Expand
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Highly Cited
2001
Highly Cited
2001
AIMS (3'R,5'S)-trans-3'-hydroxycotinine (3-HC) is a major metabolite of nicotine. The aim of this study was to characterize the… Expand
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1999
1999
trans-3'-Hydroxycotinine (THOC) has been recognized as the most abundant metabolite of nicotine. In an attempt to assess THOC and… Expand
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Highly Cited
1996
Highly Cited
1996
Nicotine is primarily metabolized to cotinine, and cotinine is further metabolized to trans-3'-hydroxycotinine in human liver… Expand
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Highly Cited
1993
Highly Cited
1993
Sperm samples from 44 cigarette smokers and 50 nonsmokers attending an infertility clinic were examined by high-performance… Expand
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Highly Cited
1992
Highly Cited
1992
Urinary nicotine metabolic output was profiled for 11 smokers who smoked their regular cigarette brands ad libitum. Thermospray… Expand
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