tramadol hydrochloride

Known as: Tramadol Hydrochloride [Chemical/Ingredient], hydrochloride tramadol, tramadol hcl 
A synthetic codeine analogue, Tramadol Hydrochloride has central analgesic properties with effects similar to opioids, such as morphine and codeine… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2017
0102019812017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Tramadol (Ultram, Ultracet) is a centrally acting synthetic opioid with analgesic efficacy comparable to codeine. Antinociception… (More)
Is this relevant?
2009
2009
OBJECTIVE-To determine the thermal antinociceptive effect of oral administration of tramadol hydrochloride at doses between 0.5… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The effect of concentration of hydrophilic (hydroxypropyl methylcellulose [HPMC]) and hydrophobic polymers (hydrogenated castor… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2003
2003
In 1994, the Drug Abuse Advisory Committee (DAAC) of the Food and Drug Administration (FDA) concluded that Ultram (tramadol… (More)
Is this relevant?
2002
2002
1. Metabolism of the analgesic agent tramadol hydrochloride has been investigated after a single oral administration of tramadol… (More)
Is this relevant?
2001
2001
An inert matrix to control the release of tramadol HCl was prepared using glyceryl behenate as a matrix-forming agent. The… (More)
Is this relevant?
2001
2001
1. Metabolism of the analgesic agent, tramadol hydrochloride, was investigated after a single oral administration of 14C-tramadol… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The present study was conducted to characterise the centrally active analgesic drug tramadol hydrochloride [(1RS,2RS)-2… (More)
  • table 1
  • table 2
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Tramadol hydrochloride produced dose-related antinociception in mouse abdominal constriction [ED50 = 1.9 (1.2-2.6) mg/kg i.p… (More)
Is this relevant?
1981
1981
Following p.o. administration of 14C-labelled rac.-1-(e)-(m-methoxyphenyl)-2-(e)-dimethylaminomethyl-cyclohexan-1-(a)-ol… (More)
Is this relevant?