Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

tomaymycin

Known as: 2-ethylidene-1,2,3,10,11,11a-hexahydro-8-hydroxy- 7,11-dimethoxy-5H-pyrrolo(2,1-c)(1,4)benzodiazepin- 5-one 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
ABSTRACT Tomaymycin produced by Streptomyces achromogenes is a naturally produced pyrrolobenzodiazepine (PBD). The biosynthetic… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1992
1992
A template-directed approach to the design of a DNA-DNA interstrand cross-linker based upon the structure of a bis-tomaymycin… Expand
Is this relevant?
1990
1990
Tomaymycin is a member of the pyrrolo[1,4]benzodiazepine [P(1,4)B] antitumor antibiotic group. This antibiotic is proposed to… Expand
Is this relevant?
1988
1988
Tomaymycin is a member of the pyrrolo[1,4]benzodiazepine antitumor-antibiotic group that binds covalently to the exocyclic 2… Expand
Is this relevant?
1986
1986
Tomaymycin is an antibiotic belonging to the pyrrolo[1,4]benzodiazepine group of antitumor compounds. Previous studies have shown… Expand
Is this relevant?
1983
1983
The structure of an antitumor antibiotic, tomaymycin, was determined as (11R, 11aS) (E)-2-ethylidene-2, 3, 5, 10, 11, 11a… Expand
Is this relevant?
Highly Cited
1981
Highly Cited
1981
The pyrrol[1,4]benzodiazepine antibiotics anthramycin, tomaymycin, sibiromycin, and neothramycins A and B are potent antitumor… Expand
Is this relevant?
1977
1977
Anthramycin, tomaymycin and sibiromycin are pyrrolo(1,4)benzodiazepine antitumor antibiotics. These compounds react with DNA and… Expand
Is this relevant?
Highly Cited
1972
Highly Cited
1972
Tomaymycin, a new antiphage antibiotic is produced by cultivation of Streptomyces achromogenes var. tomaymyceticus in a lactose… Expand
Is this relevant?
1972
1972
The mode of action of tomaymycin (TM) which is a new antibiotic with antitumor activity was studied. Inhibition of the… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 6
Is this relevant?