tocilizumab

Known as: MRA, Immunoglobulin G1, Anti-(Human Interleukin 6 Receptor) (Human-Mouse Monoclonal MRA Heavy Chain), Disulfide with Human-Mouse Monoclonal MRA Kappa-Chain, Dimer, Atlizumab 
A recombinant, humanized IgG1 monoclonal antibody directed against the interleukin-6 receptor (IL-6R) with immunosuppressant activity. Tocilizumab… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
1874 Sleep duration and quality are associated with immune markers, self-rated health, and mortality in a large cohort (NHANES… (More)
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Review
2017
Review
2017
Interleukin-6 (IL-6) is a pleiotropic cytokine that not only regulates the immune and inflammatory response but also affects… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Systemic juvenile idiopathic arthritis (JIA) is the most severe subtype of JIA; treatment options are limited… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The anti-interleukin (IL) 6 receptor antibody tocilizumab inhibits signalling of IL6, a key cytokine in rheumatoid… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVES The phase III RADIATE study examined the efficacy and safety of tocilizumab, an anti-IL-6 receptor monoclonal antibody… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE To examine the efficacy and safety of the humanized anti-interleukin-6 receptor antibody tocilizumab combined with… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Systemic-onset juvenile idiopathic arthritis does not always respond to available treatments, including antitumour… (More)
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Highly Cited
2007
Highly Cited
2007
The sparsity which is implicit in MR images is exploited to significantly undersample k-space. Some MR images such as angiograms… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE To evaluate the ability of tocilizumab (a humanised anti-IL-6 receptor antibody) monotherapy to inhibit progression of… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To establish the safety and efficacy of repeat infusions of tocilizumab (previously known as MRA), a humanized anti… (More)
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