tizanidine

Known as: Tizanidinum, tizanidine [Chemical/Ingredient], 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2017
0102019812017

Papers overview

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2009
2009
BACKGROUND While spasticity is commonly treated with oral agents or botulinum neurotoxin (BoNT) injection, these treatments have… (More)
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2005
2005
BACKGROUND AND OBJECTIVE Oral contraceptives (OCs) can inhibit drug metabolism, but their effect on various cytochrome P450 (CYP… (More)
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2004
2004
AIMS To identify the cytochrome p450 (CYP) enzyme(s) that catalyze the metabolism of tizanidine in vitro. METHODS The effect of… (More)
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2002
2002
OBJECTIVE To assess the efficacy of tizanidine hydrochloride versus placebo as adjunctive prophylactic therapy for chronic daily… (More)
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1994
1994
This multicenter, stratified, randomized, placebo-controlled, double-blind trial evaluated tizanidine for use in the United… (More)
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1994
1994
This investigation estimated the mechanisms of tizanidine action on spasticity using a battery of neurophysiological methods… (More)
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1994
1994
Tizanidine, an imidazoline that acts as an agonist at alpha 2-adrenergic receptors, has been shown to be effective in reducing… (More)
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1986
1986
In a double-blind study the efficacy and tolerability of tizanidine was compared with those of carbamazepine in the management of… (More)
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1984
1984
Neurophysiological investigations of a patient suffering from the stiff-man syndrome revealed that exteroceptive reflexes, in… (More)
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1982
1982
A double-blind crossover trial compared tizanidine with baclofen in 36 patients with spasticity. Tizanidine appeared to reduce… (More)
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