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tirilazad mesylate hydrate

Known as: 21-(4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methylpregna-1,4,9(11)-triene-3,20-dione monomethane sulfonate, tirilazad mesylate 
 
National Institutes of Health

Papers overview

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Review
2008
Review
2008
In the United States stroke is the third leading cause of death and the leading cause of disability. Brain injury following… Expand
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Highly Cited
1998
Highly Cited
1998
Objective.\p=m-\Tocompare the efficacy of methylprednisolone administered for 24 hours with methyprednisolone administered for 48… Expand
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Highly Cited
1998
Highly Cited
1998
Object. A randomized double-blind clinical trial was conducted to compare neurological and functional recovery and morbidity and… Expand
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Highly Cited
1998
Highly Cited
1998
OBJECT A randomized double-blind clinical trial was conducted to compare neurological and functional recovery and morbidity and… Expand
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Highly Cited
1998
Highly Cited
1998
OBJECT The authors prospectively studied the efficacy of tirilazad mesylate, a novel aminosteroid, in humans with head injuries… Expand
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Highly Cited
1997
Highly Cited
1997
Objective. —To compare the efficacy of methylprednisolone administered for 24 hours with methyprednisolone administered for 48… Expand
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Highly Cited
1997
Highly Cited
1997
OBJECTIVE To compare the efficacy of methylprednisolone administered for 24 hours with methyprednisolone administered for 48… Expand
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Highly Cited
1997
Highly Cited
1997
To test the safety and efficacy of tirilazad mesylate, a nonglucocorticoid 21-aminosteroid, in improving the outcome of patients… Expand
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Highly Cited
1996
Highly Cited
1996
Tirilazad mesylate, a nonglucocorticoid 21-aminosteroid, has been shown in experimental models to reduce vasospasm following… Expand
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Review
1992
Review
1992
Oxygen radical-mediated lipid peroxidation (LP) has been suggested increasingly to be an important factor in posttraumatic… Expand
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