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tirilazad mesylate hydrate

Known as: 21-(4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methylpregna-1,4,9(11)-triene-3,20-dione monomethane sulfonate, tirilazad mesylate 
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Highly Cited
1998
Highly Cited
1998
Objective.\p=m-\Tocompare the efficacy of methylprednisolone administered for 24 hours with methyprednisolone administered for 48… 
Highly Cited
1998
Highly Cited
1998
OBJECT A randomized double-blind clinical trial was conducted to compare neurological and functional recovery and morbidity and… 
Highly Cited
1998
Highly Cited
1998
Object. A randomized double-blind clinical trial was conducted to compare neurological and functional recovery and morbidity and… 
Highly Cited
1998
Highly Cited
1998
OBJECT The authors prospectively studied the efficacy of tirilazad mesylate, a novel aminosteroid, in humans with head injuries… 
Highly Cited
1997
Highly Cited
1997
Objective. —To compare the efficacy of methylprednisolone administered for 24 hours with methyprednisolone administered for 48… 
Highly Cited
1997
Highly Cited
1997
OBJECTIVE To compare the efficacy of methylprednisolone administered for 24 hours with methyprednisolone administered for 48… 
Highly Cited
1997
Highly Cited
1997
To test the safety and efficacy of tirilazad mesylate, a nonglucocorticoid 21-aminosteroid, in improving the outcome of patients… 
Highly Cited
1996
Highly Cited
1996
Tirilazad mesylate, a nonglucocorticoid 21-aminosteroid, has been shown in experimental models to reduce vasospasm following… 
Review
1992
Review
1992
Oxygen radical-mediated lipid peroxidation (LP) has been suggested increasingly to be an important factor in posttraumatic…