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tirilazad mesylate hydrate

Known as: 21-(4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methylpregna-1,4,9(11)-triene-3,20-dione monomethane sulfonate, tirilazad mesylate 
National Institutes of Health

Papers overview

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Review
2008
Review
2008
In the United States stroke is the third leading cause of death and the leading cause of disability. Brain injury following… Expand
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Highly Cited
2000
Highly Cited
2000
Five parkinsonian patients were transplanted bilaterally into the putamen and caudate nucleus with human embryonic mesencephalic… Expand
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Highly Cited
1998
Highly Cited
1998
Object. A randomized double-blind clinical trial was conducted to compare neurological and functional recovery and morbidity and… Expand
Highly Cited
1998
Highly Cited
1998
Objective.\p=m-\Tocompare the efficacy of methylprednisolone administered for 24 hours with methyprednisolone administered for 48… Expand
Highly Cited
1998
Highly Cited
1998
OBJECT A randomized double-blind clinical trial was conducted to compare neurological and functional recovery and morbidity and… Expand
Highly Cited
1997
Highly Cited
1997
Objective. —To compare the efficacy of methylprednisolone administered for 24 hours with methyprednisolone administered for 48… Expand
Highly Cited
1997
Highly Cited
1997
OBJECTIVE To compare the efficacy of methylprednisolone administered for 24 hours with methyprednisolone administered for 48… Expand
Highly Cited
1997
Highly Cited
1997
To test the safety and efficacy of tirilazad mesylate, a nonglucocorticoid 21-aminosteroid, in improving the outcome of patients… Expand
Highly Cited
1996
Highly Cited
1996
Tirilazad mesylate, a nonglucocorticoid 21-aminosteroid, has been shown in experimental models to reduce vasospasm following… Expand
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Review
1992
Review
1992
Oxygen radical-mediated lipid peroxidation (LP) has been suggested increasingly to be an important factor in posttraumatic… Expand