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tiotidine

Known as: 2-guanidino-4-(2-(2-cyano-3-methylguanidino)ethylthiomethyl)thiazole, N-(2-(((2-((aminoiminomethyl)amino)-4-thiazoyl) methyl)thio)ethyl)-N'-cyano-N''-methylguanidine 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (2)

CimetidineHistamine H2 Antagonists

Narrower (4)

ICI 125,211tiotidine monofumaratetiotidine monohydrochloridetiotidine monomaleate
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Tiotidine, a classical H2-antagonist, presents characteristics of an inverse agonist in U937 cell line
It is generally accepted that the histamine H 2 receptor is coupled to the adenylyl cyclase system through direct interaction… 
1987
1987
Differential effects of histamine receptor antagonists on human natural killer cell activity.
In this study we investigated the modulation of natural killer (NK) cell activity by various histamine receptor antagonists in… 
1986
1986
Is [3H]-tiotidine a specific ligand for the H2-receptor?
The H2-antagonist tiotidine inhibited the H2-receptor-mediated, histamine-induced increase in cyclic AMP in dispersed mucosal… 
1985
1985
Pharmacological analysis of the pentagastrin‐tiotidine interaction in the mouse isolated stomach
1 The pentagastrin‐tiotidine interaction has been analysed, using improved techniques, in the mouse isolated, lumen‐perfused… 
1984
1984
Release of Histamine by Sympathetic Nerve Stimulation in the Guinea Pig Heart and Modulation of Adrenergic Responses: A Physiological Role for Cardiac Histamine?
Histamine has been reported to attenuate adrenergic responses in cardiovascular tissues. In guinea pig atria preloaded with [3H… 
1984
1984
Inhibition of mono-oxygenase and oxidase activity of rat-hepatic cytochrome P-450 by H2-receptor blockers.
Of four H2 blockers, cimetidine, tiotidine, oxmetidine and ranitidine, all except ranitidine showed ligand (type II) interactions… 
1983
1983
Conformational requirements for histamine H2-receptor inhibitors: a structure-activity study of phenylene analogues related to cimetidine and tiotidine.
Two series of compounds related to cimetidine and tiotidine were synthesized as part of a study to evaluate the importance of… 
1983
1983
Effect of some new H2-receptor antagonists on gastrointestinal motility
Some new histamine H2-receptor antagonists were tested for their effects on gastrointestinal motility. Ranitidine was found to… 
1981
1981
Tiotidine and cimetidine—kinetics and dynamics
Tiotidine and Cimetidine kinetics and dynamics were compared to assess mechanisms of the longer duration of effect of tiotidine… 
1981
1981
Effect of some new histamine H2-receptor antagonists on the guinea-pig papillary muscle
SummarySeveral histamine H2-receptor antagonists (cimetidine, ranitidine, oxmetidine and tiotidine) were tested for their… 
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