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tigecycline

Known as: 9-(tert-butylglycylamido)minocycline, Tigecyclinum, tigecycline [Chemical/Ingredient] 
A broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Carbapenems are considered as last-resort antibiotics for the treatment of infections caused by multidrug-resistant Gram-negative… Expand
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Review
2018
Review
2018
Vancomycin-resistant enterococci (VRE) are important nosocomial pathogens. Invasive VRE infections are difficult to treat since… Expand
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Review
2018
Review
2018
BACKGROUND Rates of colonization and infection with carbapenem-resistant Gram-negative pathogens are on the rise, particularly in… Expand
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Highly Cited
2007
Highly Cited
2007
ABSTRACT In the setting of catheter-related bloodstream infections, intraluminal antibiotic lock therapy could be useful for the… Expand
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Review
2006
Review
2006
The increasing trend of carbapenem resistance in Acinetobacter baumannii worldwide is a concern since it limits drastically the… Expand
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Review
2006
Review
2006
Tigecycline (GAR-936) is the first glycylcycline antibiotic to be approved by the US Food and Drug Administration (FDA). The drug… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT Tigecycline, a novel glycylcycline antibiotic, exhibits strong activity against gram-positive, gram-negative, aerobic… Expand
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Review
2005
Review
2005
  • D. Livermore
  • The Journal of antimicrobial chemotherapy
  • 2005
  • Corpus ID: 11160727
Tigecycline is the first glycylcycline to be launched and is one of the very few new antimicrobials with activity against Gram… Expand
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Highly Cited
2005
Highly Cited
2005
This pooled analysis includes 2 phase 3, double-blind trials designed to evaluate the safety and efficacy of tigecycline, versus… Expand
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Highly Cited
2003
Highly Cited
2003
ABSTRACT Pseudomonas aeruginosa strains are less susceptible to tigecycline (previously GAR-936; MIC, 8 μg/ml) than many other… Expand
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