tigecycline

Known as: 9-(tert-butylglycylamido)minocycline, Tigecyclinum, tigecycline [Chemical/Ingredient] 
A broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the… (More)
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
BACKGROUND On the basis of noninferiority trials, tigecycline received Food and Drug Administration (FDA) approval in 2005. In… (More)
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Highly Cited
2008
Highly Cited
2008
Eighteen patients received tigecycline as treatment for infection due to multidrug-resistant gram-negative bacilli, including… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVES Multidrug-resistant (MDR) Acinetobacter baumannii is increasing in our hospital and worldwide, raising the necessity… (More)
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Highly Cited
2007
Highly Cited
2007
Tigecycline has an extended spectrum of in vitro antimicrobial activities, including that against multidrug-resistant… (More)
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Review
2006
Review
2006
Tigecycline (GAR-936) is the first glycylcycline antibiotic to be approved by the US Food and Drug Administration (FDA). The drug… (More)
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Review
2005
Review
2005
Tigecycline is the first glycylcycline to be launched and is one of the very few new antimicrobials with activity against Gram… (More)
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Review
2005
Review
2005
  • Gary Noskin
  • Clinical infectious diseases : an official…
  • 2005
Tigecycline is a new semisynthetic glycylcycline for the treatment of serious infections. Of the glycylcyclines, tigecycline is… (More)
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Highly Cited
2005
Highly Cited
2005
Two phase 3, double-blind studies in hospitalized adults with complicated skin and skin-structure infections (cSSSI) determined… (More)
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Highly Cited
2005
Highly Cited
2005
This pooled analysis includes 2 phase 3, double-blind trials designed to evaluate the safety and efficacy of tigecycline, versus… (More)
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Highly Cited
2005
Highly Cited
2005
Tigecycline, a novel glycylcycline antibiotic, exhibits strong activity against gram-positive, gram-negative, aerobic, anaerobic… (More)
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