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thyroid hormone transport
The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC…
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National Institutes of Health
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Papers overview
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Review
2015
Review
2015
Thyroid hormone transporters—functions and clinical implications
J. Bernal
,
A. Guadaño-Ferraz
,
B. Morte
Nature Reviews Endocrinology
2015
Corpus ID: 24015865
The cellular influx and efflux of thyroid hormones are facilitated by transmembrane protein transporters. Of these transporters…
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Highly Cited
2013
Highly Cited
2013
Sulfated Metabolites of Polychlorinated Biphenyls Are High-Affinity Ligands for the Thyroid Hormone Transport Protein Transthyretin
Fabian A. Grimm
,
H. Lehmler
,
Xianran He
,
L. Robertson
,
M. Duffel
Environmental Health Perspectives
2013
Corpus ID: 5022379
Background: The displacement of l-thyroxine (T4) from binding sites on transthyretin (TTR) is considered a significant…
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Review
2012
Review
2012
The monocarboxylate transporter family—Role and regulation
A. Halestrap
,
Marieangela C Wilson
IUBMB Life - A Journal of the International Union…
2012
Corpus ID: 14524985
Monocarboxylate transporter (MCT) isoforms 1–4 catalyze the proton‐linked transport of monocarboxylates such as L‐lactate across…
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Highly Cited
2012
Highly Cited
2012
Assessment of the binding of hydroxylated polybrominated diphenyl ethers to thyroid hormone transport proteins using a site-specific fluorescence probe.
Xiaomin Ren
,
Liang-Hong Guo
Environmental Science and Technology
2012
Corpus ID: 8092977
Polybrominated diphenyl ethers (PBDEs) have been shown to disrupt thyroid hormone (TH) functions on experimental animals, and one…
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Highly Cited
2010
Highly Cited
2010
Essential Molecular Determinants for Thyroid Hormone Transport and First Structural Implications for Monocarboxylate Transporter 8*
A. Kinne
,
G. Kleinau
,
+4 authors
U. Schweizer
Journal of Biological Chemistry
2010
Corpus ID: 205301324
Monocarboxylate transporter 8 (MCT8, SLC16A2) is a thyroid hormone (TH) transmembrane transport protein mutated in Allan-Herndon…
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Review
2009
Review
2009
Minireview: Pathophysiological importance of thyroid hormone transporters.
H. Heuer
,
T. Visser
Endocrinology
2009
Corpus ID: 20759774
Thyroid hormone metabolism and action are largely intracellular events that require transport of iodothyronines across the plasma…
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Highly Cited
2008
Highly Cited
2008
Expression of the thyroid hormone transporters monocarboxylate transporter-8 (SLC16A2) and organic ion transporter-14 (SLCO1C1) at the blood-brain barrier.
L. M. Roberts
,
K. Woodford
,
+7 authors
N. Zerangue
Endocrinology
2008
Corpus ID: 25296639
Thyroid hormones require transport across cell membranes to carry out their biological functions. The importance of transport for…
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Review
2005
Review
2005
Thyroid hormone transporters in health and disease.
J. Jansen
,
E. Friesema
,
C. Milici
,
T. Visser
Thyroid
2005
Corpus ID: 45935780
Cellular entry is required for conversion of thyroid hormone by the intracellular deiodinases and for binding of 3,3',5…
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Highly Cited
2003
Highly Cited
2003
Identification of Monocarboxylate Transporter 8 as a Specific Thyroid Hormone Transporter*
E. Friesema
,
Š. Ganguly
,
Amal Abdalla
,
Jocelyn E. Manning Fox
,
A. Halestrap
,
T. Visser
Journal of Biological Chemistry
2003
Corpus ID: 16743453
Transport of thyroid hormone across the cell membrane is required for its action and metabolism. Recently, a T-type amino acid…
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Highly Cited
2001
Highly Cited
2001
Thyroid Hormone Transport by the Heterodimeric Human System L Amino Acid Transporter.
E. Friesema
,
R. Docter
,
+4 authors
T. Visser
Endocrinology
2001
Corpus ID: 7972686
Transport of thyroid hormone across the cell membrane is required for thyroid hormone action and metabolism. We have investigated…
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