thymine glycol

Known as: 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydroxydihydrothymine, glycolthymine 
 
National Institutes of Health

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2009
2009
Localized clustering of damage is a hallmark of certain DNA-damaging agents, particularly ionizing radiation. The potential for… (More)
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2004
2004
DNA damage created by reactive oxygen species includes the prototypic oxidized pyrimidine, thymine glycol (Tg), which exists in… (More)
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2003
2003
DNA polymerase zeta (Polzeta) promotes the mutagenic bypass of DNA lesions in eukaryotes. Genetic studies in Saccharomyces… (More)
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1998
1998
An ultrasensitive assay for measuring DNA base damage is described that couples immunochemical recognition with capillary… (More)
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Highly Cited
1997
Highly Cited
1997
Xeroderma pigmentosum (XP) patients fail to remove pyrimidine dimers caused by sunlight and, as a consequence, develop multiple… (More)
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Review
1989
Review
1989
Progress in identifying the important endogenous processes damaging DNA and developing methods to assay this damage in… (More)
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Highly Cited
1988
Highly Cited
1988
Oxidative damage to DNA is caused by reactive by-products of normal metabolism, as well as by radiation. Oxidized DNA bases… (More)
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1988
1988
Thymine glycol (5,6-dihydroxy-5,6-dihydrothymine) is a base damage common to oxidative mutagens and the major stable radiolysis… (More)
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1985
1985
Single-stranded DNA of coliphage M13mp8 was treated with the oxidizing agent, KMnO4, under conditions that selectively form cis-5… (More)
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Highly Cited
1984
Highly Cited
1984
Thymine glycol is a DNA damage product of ionizing radiation and other oxidative mutagens. In an attempt to find a noninvasive… (More)
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