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thymidylate kinase
Known as:
TMP kinase
, thymidylate monophosphate kinase
, dTMP kinase
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National Institutes of Health
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Related topics
Related topics
3 relations
DTYMK gene
Narrower (1)
Dtymk protein, mouse
Broader (1)
Nucleoside-Phosphate Kinase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Rational Design and 3D-Pharmacophore Mapping of 5′-Thiourea-Substituted α-Thymidine Analogues as Mycobacterial TMPK Inhibitors
C. Andrade
,
K. Pasqualoto
,
E. Ferreira
,
A. Hopfinger
J. Chem. Inf. Model.
2009
Corpus ID: 15944753
Thymidine monophosphate kinase (TMPK) has emerged as an attractive target for developing inhibitors of Mycobacterium tuberculosis…
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2008
2008
Identification of a putative human mitochondrial thymidine monophosphate kinase associated with monocytic/macrophage terminal differentiation
Yen-Ling Chen
,
Da-wei Lin
,
Z. Chang
Genes to cells : devoted to molecular & cellular…
2008
Corpus ID: 11680631
Mitochondrial DNA synthesis requires the supply of thymidine triphosphate (dTTP) independent of nuclear DNA replication. In…
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Highly Cited
2007
Highly Cited
2007
Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth.
Ineke van Daele
,
H. Munier-Lehmann
,
M. Froeyen
,
J. Balzarini
,
S. van Calenbergh
Journal of medicinal chemistry
2007
Corpus ID: 33147828
Recently, thymidine monophosphate kinase (TMPK) emerged as an attractive target for developing inhibitors of Mycobacterium…
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2006
2006
3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.
V. Aparna
,
J. Jeevan
,
M. Ravi
,
G. Desiraju
,
B. Gopalakrishnan
Bioorganic & medicinal chemistry letters
2006
Corpus ID: 45353769
Highly Cited
2005
Highly Cited
2005
Activity profiles of deoxynucleoside kinases and 5'-nucleotidases in cultured adipocytes and myoblastic cells: insights into mitochondrial toxicity of nucleoside analogs.
S. Rylova
,
F. Albertioni
,
G. Flygh
,
S. Eriksson
Biochemical pharmacology
2005
Corpus ID: 39260326
Highly Cited
2003
Highly Cited
2003
Enzymatic and Structural Analysis of Inhibitors Designed against Mycobacterium tuberculosis Thymidylate Kinase
A. Haouz
,
V. Vanheusden
,
+4 authors
M. Delarue
The Journal of Biological Chemistry
2003
Corpus ID: 21258868
The chemical synthesis of new compounds designed as inhibitors of Mycobacterium tuberculosis TMP kinase (TMPK) is reported. The…
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Highly Cited
2003
Highly Cited
2003
3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
V. Vanheusden
,
H. Munier-Lehmann
,
+7 authors
S. van Calenbergh
Journal of medicinal chemistry
2003
Corpus ID: 3331985
Thymidine monophosphate kinase (TMPK) of Mycobacterium tuberculosis (TMPKmt) represents an attractive target for blocking the…
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Highly Cited
2003
Highly Cited
2003
Comparative Study of Purine and Pyrimidine Nucleoside Analogues Acting on the Thymidylate Kinases of Mycobacterium tuberculosis and of Humans
S. Pochet
,
L. Dugué
,
G. Labesse
,
M. Delepierre
,
H. Munier-Lehmann
Chembiochem : a European journal of chemical…
2003
Corpus ID: 15149031
Thymidine monophosphate kinase (TMPK) from Mycobacterium tuberculosis (TMPKmt) is an attractive target for the design of specific…
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Highly Cited
1997
Highly Cited
1997
Fidelity of Escherichia coli DNA Polymerase III Holoenzyme
L. Bloom
,
Xiluo Chen
,
D. Fygenson
,
J. Turner
,
M. O’Donnell
,
M. Goodman
The Journal of Biological Chemistry
1997
Corpus ID: 19529634
The fidelity of Escherichia coli DNA polymerase III (pol III) is measured and the effects of β, γ processivity and ε proofreading…
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1996
1996
Comparative metabolism of Mesoplasma, Entomoplasma, Mycoplasma, and Acholeplasma.
J. Pollack
,
M. Williams
,
J. Banzon
,
M. Jones
,
L. Harvey
,
J. Tully
International journal of systematic bacteriology
1996
Corpus ID: 15077989
Cytoplasmic fractions from species of the Mollicutes genera Entomoplasma, Mesoplasma, Mycoplasma, and Acholeplasma were assayed…
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