thymidylate kinase

Known as: TMP kinase, thymidylate monophosphate kinase, dTMP kinase 
 
National Institutes of Health

Related topics

Related topics

3 relations
DTYMK gene

Narrower (1)

Dtymk protein, mouse

Broader (1)

Nucleoside-Phosphate Kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Identification of novel antimycobacterial chemical agents through the in silico multi-conformational structure-based drug screening of a large-scale chemical library.
The increasing prevalence of drug-resistant tuberculosis, which is resistant to effective multiple antibiotic, presents a major… (More)
Is this relevant?
2006
2006
3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.
Three dimensional quantitative structure-activity relationship (3D-QSAR) studies were carried out on deoxythymidine monophosphate… (More)
Is this relevant?
2005
2005
Activity profiles of deoxynucleoside kinases and 5'-nucleotidases in cultured adipocytes and myoblastic cells: insights into mitochondrial toxicity of nucleoside analogs.
Nucleoside reverse transcriptase inhibitor (NRTI) treatment of HIV is associated with complications, including lipodystrophy (LD… (More)
Is this relevant?
2004
2004
Mutagenic properties of 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene, a persistent acetylaminofluorene-derived DNA adduct in mammalian cells.
The carcinogen 2-acetylaminofluorene is metabolically activated in cells and reacts with DNA to form N-(deoxyguanosin-8-yl)-2… (More)
Is this relevant?
2003
2003
Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism.
The chemical synthesis of new compounds designed as inhibitors of Mycobacterium tuberculosis TMP kinase (TMPK) is reported. The… (More)
  • table I
  • figure 1
  • table II
  • table III
  • figure 2
Is this relevant?
2003
2003
Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans.
Thymidine monophosphate kinase (TMPK) from Mycobacterium tuberculosis (TMPKmt) is an attractive target for the design of specific… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
Is this relevant?
2003
2003
3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Thymidine monophosphate kinase (TMPK) of Mycobacterium tuberculosis (TMPKmt) represents an attractive target for blocking the… (More)
  • table 1
Is this relevant?
1997
1997
Fidelity of Escherichia coli DNA polymerase III holoenzyme. The effects of beta, gamma complex processivity proteins and epsilon proofreading exonuclease on nucleotide misincorporation efficiencies.
The fidelity of Escherichia coli DNA polymerase III (pol III) is measured and the effects of beta, gamma processivity and epsilon… (More)
Is this relevant?
1996
1996
Comparative metabolism of Mesoplasma, Entomoplasma, Mycoplasma, and Acholeplasma.
Cytoplasmic fractions from species of the Mollicutes genera Entomoplasma, Mesoplasma, Mycoplasma, and Acholeplasma were assayed… (More)
  • table 1
  • table 3
  • table 4
Is this relevant?
1987
1987
An optimized thymidylate kinase assay, based on enzymatically synthesized 5-[125I]iododeoxyuridine monophosphate and its application to an immunological study of herpes simplex virus thymidine…
The biological synthesis and purification of 5-[125I]iododeoxyuridine monophosphate (IdUMP) are described. The specificity of… (More)
Is this relevant?