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thymidylate kinase

Known as: TMP kinase, thymidylate monophosphate kinase, dTMP kinase 
National Institutes of Health

Related topics

Related topics

3 relations
DTYMK gene

Narrower (1)

Dtymk protein, mouse

Broader (1)

Nucleoside-Phosphate Kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Rational Design and 3D-Pharmacophore Mapping of 5′-Thiourea-Substituted α-Thymidine Analogues as Mycobacterial TMPK Inhibitors
Thymidine monophosphate kinase (TMPK) has emerged as an attractive target for developing inhibitors of Mycobacterium tuberculosis… 
2008
2008
Identification of a putative human mitochondrial thymidine monophosphate kinase associated with monocytic/macrophage terminal differentiation
Mitochondrial DNA synthesis requires the supply of thymidine triphosphate (dTTP) independent of nuclear DNA replication. In… 
Highly Cited
2007
Highly Cited
2007
Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth.
Recently, thymidine monophosphate kinase (TMPK) emerged as an attractive target for developing inhibitors of Mycobacterium… 
2006
2006
3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.
Highly Cited
2005
Highly Cited
2005
Activity profiles of deoxynucleoside kinases and 5'-nucleotidases in cultured adipocytes and myoblastic cells: insights into mitochondrial toxicity of nucleoside analogs.
Highly Cited
2003
Highly Cited
2003
Enzymatic and Structural Analysis of Inhibitors Designed against Mycobacterium tuberculosis Thymidylate Kinase
The chemical synthesis of new compounds designed as inhibitors of Mycobacterium tuberculosis TMP kinase (TMPK) is reported. The… 
Highly Cited
2003
Highly Cited
2003
3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Thymidine monophosphate kinase (TMPK) of Mycobacterium tuberculosis (TMPKmt) represents an attractive target for blocking the… 
Highly Cited
2003
Highly Cited
2003
Comparative Study of Purine and Pyrimidine Nucleoside Analogues Acting on the Thymidylate Kinases of Mycobacterium tuberculosis and of Humans
Thymidine monophosphate kinase (TMPK) from Mycobacterium tuberculosis (TMPKmt) is an attractive target for the design of specific… 
Highly Cited
1997
Highly Cited
1997
Fidelity of Escherichia coli DNA Polymerase III Holoenzyme
The fidelity of Escherichia coli DNA polymerase III (pol III) is measured and the effects of β, γ processivity and ε proofreading… 
1996
1996
Comparative metabolism of Mesoplasma, Entomoplasma, Mycoplasma, and Acholeplasma.
Cytoplasmic fractions from species of the Mollicutes genera Entomoplasma, Mesoplasma, Mycoplasma, and Acholeplasma were assayed… 
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