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thymidylate kinase activity
Known as:
thymidylate monophosphate kinase activity
, thymidine monophosphate kinase activity
, thymidine 5'-monophosphate kinase activity
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Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate. [EC:2.7.4.9]
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase.
B. Degrève
,
R. Esnouf
,
E. De Clercq
,
J. Balzarini
Molecular Pharmacology
2001
Corpus ID: 28314063
The broad substrate specificity of herpes simplex virus type 1 (HSV-1) thymidine kinase (TK) has provided the basis for selective…
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Highly Cited
1998
Highly Cited
1998
The Epstein-Barr Virus Thymidine Kinase Does Not Phosphorylate Ganciclovir or Acyclovir and Demonstrates a Narrow Substrate Specificity Compared to the Herpes Simplex Virus Type 1 Thymidine Kinase
E. Gustafson
,
A. Chillemi
,
D. Sage
,
J. Fingeroth
Antimicrobial Agents and Chemotherapy
1998
Corpus ID: 21479634
ABSTRACT The Epstein-Barr virus (EBV) thymidine kinase (TK) was expressed in mammalian 143B TK− cells to investigate its…
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Highly Cited
1984
Highly Cited
1984
The CDC8 gene of yeast encodes thymidylate kinase.
A. Jong
,
C. Kuo
,
J. Campbell
Journal of Biological Chemistry
1984
Corpus ID: 2956785
1979
1979
Characterization of pyrimidine deoxyribonucleoside kinase (thymidine kinase) and thymidylate kinase as a multifunctional enzyme in cells transformed by herpes simplex virus type 1 and in cells…
M. S. Chen
,
W. P. Summers
,
J. Walker
,
W. Summers
,
W. Prusoff
Journal of Virology
1979
Corpus ID: 23564117
Pyrimidine deoxyribonucleoside kinase (thymidine kinase [TK]) was purified from two herpes simplex virus type 1 (HVS-1…
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Highly Cited
1978
Highly Cited
1978
Association of thymidylate kinase activity with pyrimidine deoxyribonucleoside kinase induced by herpes simplex virus.
M. S. Chen
,
W. Prusoff
Journal of Biological Chemistry
1978
Corpus ID: 628276
Thymidine kinase derived from LMTK+ does not exhibit thymidylate kinase activity. However, protein isolated by affinity column…
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1971
1971
Increase of thymidine, thymidylate and deoxycytidine kinase activites during germination of bacterial spores.
H. Tanooka
,
H. Terano
,
H. Otsuka
Biochimica et Biophysica Acta
1971
Corpus ID: 39358188
1965
1965
The synergistic anti-neoplastic activity of combinations of mitomycins with either 6-thioguanine or 5-fluorouracil.
A. Sartorelli
,
B. Booth
Cancer Research
1965
Corpus ID: 14023474
Summary Mitomycin C or porfiromycin (methyl mitomycin) in combination with either 6-thioguanine or 5-fluorouracil produced…
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1964
1964
METABOLIC ALTERATIONS AFTER TOTAL BODY DOSES OF X-RADIATION. EFFECT OF IRRADIATION OF NORMAL LIVER ON DNA SYNTHESIS AFTER PARTIAL HEPATECTOMY.
N. Fausto
,
T. Uchiyama
,
J. Vanlancker
Archives of Biochemistry and Biophysics
1964
Corpus ID: 37870560
Highly Cited
1960
Highly Cited
1960
Stabilization of Thymidylate Kinase Activity by Thymidylate and by Thymidine
T. Bojarski
,
H. Hiatt
Nature
1960
Corpus ID: 4145503
WE have recently reported that an increase in thymidylate kinase activity occurs in rat liver and kidney following injection of…
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Highly Cited
1960
Highly Cited
1960
Stimulation of thymidylate kinase activity in rat tissues by thymidine administration.
H. Hiatt
,
T. Bojarski
Biochemical and Biophysical Research…
1960
Corpus ID: 7809851
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