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threo-pentos-2-ulose

Known as: xylosone 
National Institutes of Health

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1 relation

Broader (1)

Ketoses

Papers overview

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2015
2015
When Good Intentions Go Awry: Modification of a Recombinant Monoclonal Antibody in Chemically Defined Cell Culture by Xylosone, an Oxidative Product of Ascorbic Acid.
With the advent of new initiatives to develop chemically defined media, cell culture scientists screen many additives to improve… 
Highly Cited
2011
Highly Cited
2011
Vitamin C Degradation Products and Pathways in the Human Lens*
Vitamin C and its degradation products participate in chemical modifications of proteins in vivo through non-enzymatic glycation… 
2009
2009
Formation of pigment precursor (+)-1''-methylene-6''-hydroxy-2H-furan-5''-one-catechin isomers from (+)-catechin and a degradation product of ascorbic acid in a model wine system.
The present study investigates the contribution of ascorbic acid to the formation of pigment precursors in model white wine… 
Highly Cited
2003
Highly Cited
2003
Methylglyoxal metabolism and diabetic complications: roles of aldose reductase, glyoxalase-I, betaine aldehyde dehydrogenase and 2-oxoaldehyde dehydrogenase.
1999
1999
A systematic approach to evaluate the modification of lens proteins by glycation-induced crosslinking.
Highly Cited
1998
Highly Cited
1998
The generation of superoxide anions in glycation reactions with sugars, osones, and 3-deoxyosones.
Glycoxidation is a process whereby glycated proteins chemically generate oxygen free radicals. Superoxide anion formation was… 
Highly Cited
1997
Highly Cited
1997
Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes.
1994
1994
Determination of glycation crosslinking by the sugar-dependent incorporation of [14C]lysine into protein.
A simple, quantitative assay has been established to determine the glycation-dependent crosslinking ability of any sugar by… 
1992
1992
Glycation of MP26 and MP22 in bovine lens membranes.
Highly Cited
1991
Highly Cited
1991
High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis.
Pentosidine is a recently discovered protein crosslink, involving lysine and arginine residues linked together in an imidazo [4,5… 
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