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tetroxoprim

Known as: 2,4-diamino-5-(3,5-dimethoxy-4(2-methoxy ethoxy)benzyl)pyrimidine, 5-((3,5-dimethoxy-4-(2-methoxyethoxy)phenyl)methyl)pyrimidinediamine, piritrexin 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Anti-Infective AgentsPyrimidines
Sulfadiazine / tetroxoprim

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Structural relationships, thermal properties, and physicochemical characterization of anhydrous and solvated crystalline forms of tetroxoprim.
Six distinct phases of the antibacterial tetroxoprim (TXP) have been isolated by recrystallization from various solvents. These… 
1993
1993
History and future of antimicrobial diaminopyrimidines.
Numerous pyrimidine and purine analogs were synthesized in the late forties in G.H. Hitchings' group as potential nucleic acid… 
1993
1993
Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis
We compared Ro 11-8958, an analog of trimethoprim (TMP) with improved antimicrobial and pharmacokinetic properties, other… 
1993
1993
Differential methotrexate toxicity between two human oral squamous carcinoma cell lines.
Methotrexate is often used for induction or palliative therapy of advanced head and neck squamous cell carcinoma (HNSCC). However… 
1987
1987
In Vivo Activity of Piritrexin Against Toxoplasma gondii
1985
1985
Efficacy of tetroxoprim/sulphadiazine in the treatment of Pneumocystis carinii pneumonitis in rats.
Pneumocystis carinii pneumonitis was induced using dexamethasone in male Sprague-Dawley rats. After the first death due to Pn… 
1984
1984
Diffusion of metioprim, tetroxoprim and sulphadiazine in the cerebrospinal fluid of dogs with healthy meninges and dogs with experimental meningitis.
The diffusion of metioprim (MTP), tetroxoprim (TXP) and sulphadiazine (SDZ) in cerebrospinal fluid (CSF), following single… 
1984
1984
[Diffusion of tetroxoprim and sulfadiazine in the cerebrospinal fluid of neurosurgery patients].
Two studies were conducted in neurosurgical patients to establish cerebrospinal fluid (CSF) and plasma levels of tetroxoprim (TXP… 
Review
1983
Review
1983
Disposition and Metabolism of Trimethoprim, Tetroxoprim, Sulfamethoxazole, and Sulfadiazine
Since the antibacterial sulfonamides and their potentiators are used extensively in both human and veterinary medicine, detailed… 
1979
1979
Tetroxoprim – a new inhibitor of bacterial dihydrofolate reductase
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