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Targeting Copper Clusters Tetrathiomolybdate (TM) is a copper-depleting agent that has potential in treating copper-dependent… Expand It has become clear that serum "free" copper (the copper not bound to ceruloplasmin in the blood) is the copper causing copper… Expand
Background No consensus is available on the optimal initial treatment in Wilson disease.
The adsorption of two major molybdenum (Mo) species, molybdate (MoO4(2-)) and tetrathiomolybdate (MoS4(2-)) onto two main iron… Expand Purpose: A second-generation tetrathiomolybdate analogue (ATN-224; choline tetrathiomolybdate), which selectively binds copper… Expand Molybdenum is a nutrient important for a variety of biological functions, most notably nitrogen fixation. Molybdenum availability… Expand PURPOSE
Tetrathiomolybdate (TM), a copper-lowering agent, has been shown in preclinical murine tumor models to be antiangiogenic… Expand Copper plays an essential role in promoting angiogenesis. Tumors that become angiogenic acquire the ability to enter a phase of… Expand Preclinical and in vitro studies have determined that copper is an important cofactor for angiogenesis. Tetrathiomolybdate (TM… Expand The derivation dT on the exterior algebra of forms on a manifold M with values in the exterior algebra of forms on the tangent… Expand