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tetrahydrofolate biosynthetic process

Known as: tetrahydrofolate synthesis, tetrahydrofolate biosynthesis, tetrahydrofolate formation 
The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Genome-wide association studies (GWAS) of late-onset Alzheimer disease (LOAD) have consistently observed strong evidence of… Expand
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Review
2007
Review
2007
  • M. T. Subbiah
  • Translational research : the journal of…
  • 2007
  • Corpus ID: 45698775
The Human Genome Project and subsequent identification of single nucleotide polymorphisms (SNPs) within populations has played a… Expand
Highly Cited
2006
Highly Cited
2006
GTP cyclohydrolase I (GCYH-I) is the first enzyme of the de novo tetrahydrofolate biosynthetic pathway present in bacteria, fungi… Expand
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Highly Cited
2003
Highly Cited
2003
Tetrahydrofolate (THF) is a central cofactor for one-carbon transfer reactions in all living organisms. In this study, we… Expand
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Highly Cited
2002
Highly Cited
2002
The plant enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase/7,8-dihydropteroate synthase (HPPK/DHPS) is a mitochondrial… Expand
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Highly Cited
1993
Highly Cited
1993
Washed and air-oxidized proteins from Sporomusa ovata cleaved the C-O bond of methanol or methoxyaromatics and transferred the… Expand
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Review
1977
Review
1977
  • R. Ferone
  • Bulletin of the World Health Organization
  • 1977
  • Corpus ID: 21085700
It is known that malaria parasites are inhibited by sulfonamides and antifolate compounds, require 4-aminobenzoic acid for growth… Expand
1976
1976
Studies were undertaken to (a) assess intracellular methotrexate (MTX) levels at extracellular drug concentrations comparable to… Expand
1974
1974
Abstract Two sisters were detected with normal serum folic acid excreting formiminoglutamic acid (FIGLU) in urine in excessive… Expand