FAQ

tetrahydrofolate biosynthetic process

Known as: tetrahydrofolate synthesis, tetrahydrofolate biosynthesis, tetrahydrofolate formation 
The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2018
012319762018

Papers overview

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Highly Cited
2010
Highly Cited
2010
Dementia Revealed: Novel Chromosome 6 Locus for Late-Onset Alzheimer Disease Provides Genetic Evidence for Folate-Pathway Abnormalities
Genome-wide association studies (GWAS) of late-onset Alzheimer disease (LOAD) have consistently observed strong evidence of… (More)
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2010
2010
Evaluation of MTHFR677C>T polymorphism in prediction and prognosis of esophageal squamous cell carcinoma: a case-control study in a northern Indian population.
Early diagnosis and better prognosis of esophageal squamous cell carcinoma (ESCC) is still a challenge. Besides environmental… (More)
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2010
2010
Role of parental folate pathway single nucleotide polymorphisms in altering the susceptibility to neural tube defects in South India.
AIM To investigate the role of four parental folate pathway single nucleotide polymorphisms (SNPs) i.e., methylene… (More)
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2009
2009
Telomere length in peripheral blood mononuclear cells is associated with folate status in men.
Human chromosomes are capped by telomeres, which consist of tandem repeats of DNA and associated proteins. The length of the… (More)
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2004
2004
Abyssomicin C-A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway.
 
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2003
2003
One-carbon metabolism in plants. Regulation of tetrahydrofolate synthesis during germination and seedling development.
Tetrahydrofolate (THF) is a central cofactor for one-carbon transfer reactions in all living organisms. In this study, we… (More)
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2002
2002
Folate synthesis in higher-plant mitochondria: coupling between the dihydropterin pyrophosphokinase and the dihydropteroate synthase activities.
The plant enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase/7,8-dihydropteroate synthase (HPPK/DHPS) is a mitochondrial… (More)
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2002
2002
Characterization of genes that are synthetically lethal with ade3 or leu2 in Saccharomyces cerevisiae.
Combinations of two non-lethal mutations that result in cell death are synthetically lethal. Such a genetic relationship suggests… (More)
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1993
1993
Corrinoid-Dependent Methyl Transfer Reactions Are Involved in Methanol and 3,4-Dimethoxybenzoate Metabolism by Sporomusa ovata.
Washed and air-oxidized proteins from Sporomusa ovata cleaved the C-O bond of methanol or methoxyaromatics and transferred the… (More)
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1976
1976
Exchangeable intracellular methotrexate levels in the presence and absence of vincristine at extracellular drug concentrations relevant to those achieved in high-dose methotrexate-folinic acid…
Studies were undertaken to (a) assess intracellular methotrexate (MTX) levels at extracellular drug concentrations comparable to… (More)
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