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tetrahydrofolate biosynthetic process
Known as:
tetrahydrofolate synthesis
, tetrahydrofolate biosynthesis
, tetrahydrofolate formation
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The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Dementia Revealed: Novel Chromosome 6 Locus for Late-Onset Alzheimer Disease Provides Genetic Evidence for Folate-Pathway Abnormalities
A. Naj
,
G. Beecham
,
+14 authors
M. Pericak-Vance
PLoS genetics
2010
Corpus ID: 3244934
Genome-wide association studies (GWAS) of late-onset Alzheimer disease (LOAD) have consistently observed strong evidence of…
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Review
2007
Review
2007
Nutrigenetics and nutraceuticals: the next wave riding on personalized medicine.
M. Subbiah
Translational research : the journal of…
2007
Corpus ID: 45698775
Highly Cited
2006
Highly Cited
2006
Discovery of a New Prokaryotic Type I GTP Cyclohydrolase Family*
B. El Yacoubi
,
Shilah A. Bonnett
,
Jessica Anderson
,
M. Swairjo
,
D. Iwata‐Reuyl
,
V. de Crécy-Lagard
Journal of Biological Chemistry
2006
Corpus ID: 2931611
GTP cyclohydrolase I (GCYH-I) is the first enzyme of the de novo tetrahydrofolate biosynthetic pathway present in bacteria, fungi…
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Highly Cited
2004
Highly Cited
2004
Abyssomicin C-A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway.
Bojan Bister
,
D. Bischoff
,
+7 authors
R. Süssmuth
Angewandte Chemie
2004
Corpus ID: 31430715
Highly Cited
2003
Highly Cited
2003
One-Carbon Metabolism in Plants. Regulation of Tetrahydrofolate Synthesis during Germination and Seedling Development
Samuel Jabrin
,
S. Ravanel
,
B. Gambonnet
,
R. Douce
,
F. Rébeillé
Plant Physiology
2003
Corpus ID: 7177191
Tetrahydrofolate (THF) is a central cofactor for one-carbon transfer reactions in all living organisms. In this study, we…
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Highly Cited
2002
Highly Cited
2002
Folate synthesis in higher-plant mitochondria: coupling between the dihydropterin pyrophosphokinase and the dihydropteroate synthase activities.
J. Mouillon
,
S. Ravanel
,
R. Douce
,
F. Rébeillé
The Biochemical journal
2002
Corpus ID: 11435447
The plant enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase/7,8-dihydropteroate synthase (HPPK/DHPS) is a mitochondrial…
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Highly Cited
1993
Highly Cited
1993
Corrinoid-Dependent Methyl Transfer Reactions Are Involved in Methanol and 3,4-Dimethoxybenzoate Metabolism by Sporomusa ovata
E. Stupperich
,
R. Konle
Applied and environmental microbiology
1993
Corpus ID: 19955349
Washed and air-oxidized proteins from Sporomusa ovata cleaved the C-O bond of methanol or methoxyaromatics and transferred the…
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Review
1977
Review
1977
Folate metabolism in malaria.
R. Ferone
Bulletin of the World Health Organization
1977
Corpus ID: 21085700
It is known that malaria parasites are inhibited by sulfonamides and antifolate compounds, require 4-aminobenzoic acid for growth…
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1976
1976
Exchangeable intracellular methotrexate levels in the presence and absence of vincristine at extracellular drug concentrations relevant to those achieved in high-dose methotrexate-folinic acid…
I. Goldman
,
V. Gupta
,
J. White
,
S. Loftfield
Cancer research
1976
Corpus ID: 29098586
Studies were undertaken to (a) assess intracellular methotrexate (MTX) levels at extracellular drug concentrations comparable to…
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1974
1974
Folic acid non-dependent formiminoglutamic aciduria in two siblings.
A. Niederwieser
,
P. Giliberti
,
A. Matasović
,
S. Pluznik
,
B. Steinmann
,
K. Baerlocher
Clinica chimica acta; international journal of…
1974
Corpus ID: 25156494
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