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terbogrel

Known as: (E)-6-(3-(((Cyanoamino)((1,1- dimethylethyl)amino)methylene)amino)phenyl)-6-(3-pyridinyl)-5-hexenoic acid, 6-(3-(((Cyanoamino)((1,1-dimethylethyl)amino)methylene)amino)phenyl)-6-(3-pyridinyl)Hexenoic Acid, BIBV 308 SE 
 
National Institutes of Health

Papers overview

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2007
2007
BACKGROUND Insufficient platelet inhibition is associated with an increased cardiovascular risk in up to 30% of patients taking… Expand
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2005
2005
The pulmonary vasoconstrictor, thromboxane, may contribute to the development of pulmonary hypertension. Our objective was to… Expand
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2004
2004
AIMS To characterize the pharmacokinetics of terbogrel, a new combined thromboxane A2 (TxA2) receptor and synthase inhibitor, in… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Aspirin inhibits platelet activation and reduces atherothrombotic complications in patients at risk of myocardial… Expand
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2002
2002
BACKGROUND Circulating mediators, including thromboxane A2, the vasoconstrictor, platelet aggregant, and smooth muscle mitogen… Expand
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Review
2002
Review
2002
Past medical therapy for pulmonary arterial hypertension included the use of calcium-channel antagonists in acute vasoreactive… Expand
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Review
2002
Review
2002
Until a few years ago, "conventional" treatment for pulmonary arterial hypertension (PAH) included oral anticoagulants, calcium… Expand
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2001
2001
BM567, a sulfonylurea compound whose crystal structure is here discussed and terbogrel, are both thromboxane receptor antagonists… Expand
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2000
2000
Terbogrel, (E)-6-[4-(3-tert-butyl-2-cyanoguanidino)phenyl]-6-(3-pyridyl)hex-5 -enoic acid, C(23)H(27)N(5)O(2), a mixed… Expand
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1999
1999
A new series of omega-disubstituted alkenoic acid derivatives derived from samixogrel 5 were designed and synthesized as combined… Expand
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