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temozolomide/VNP40101M

Known as: TMZ/VNP-40101M 
 
National Institutes of Health

Papers overview

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2011
2011
Laromustine (VNP40101M; 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-(methylamino) carbonylhydrazine) is a novel sulfonylhydrazine… Expand
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2008
2008
VNP40101M (1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(2 methylamino)carbonyl] hydrazine), a novel DNA alkylating agent, is… Expand
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2008
2008
The objective of this study was to develop and manufacture a stable parenteral formulation for Phase I clinical trials of… Expand
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2007
2007
VNP40101M, or 1,2-bis(methylsulfonyl)-1-(2-choloroethyl)-2-(methylamino)carbonylhydrazine (Cloretazine), is a bifunctional… Expand
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2007
2007
A sensitive method for the determination of Cloretazine (VNP40101M) and its metabolite (VNP4090CE) with an internal standard… Expand
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2005
2005
Cloretazine {1,2-bis(methylsulfonyl)-1-[(2-chloroethyl)-2-(methylamino)carbonyl]hydrazine; VNP40101M; 101M} is a… Expand
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2005
2005
SummaryPurpose: VNP40101M is a new alkylating agent that demonstrated broad anti-tumor activity in murine tumor models. A phase I… Expand
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2003
2003
PurposeVNP40101M (1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine) is a sulfonylhydrazine prodrug… Expand
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2003
2003
PurposeTo investigate the interaction of the electrophilic species generated by the decomposition of the antineoplastic prodrug 1… Expand
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2002
2002
These studies investigated the toxicological effects of 1,2-bis (methylsulfonyl)-1-(2-chloroethyl)-2-(methylaminocarbonyl… Expand
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