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temelastine

National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Histamine H1 AntagonistsPyrimidinones

Narrower (1)

SK&F 93944

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Acute and subacute actions on human performance and interactions with diazepam of temelastine (SK & F 93944) and diphenhydramine
SummaryThirteen healthy subjects participated in a combined acute and subacute double-blind, crossover trial of two H1… 
Review
2004
Review
2004
Evaluation of mechanisms inducing thyroid toxicity and the ability of the enhanced OECD Test Guideline 407 to detect these changes
The OECD has developed an “enhanced Test Guideline 407” (TG 407) protocol for detecting endocrine effects during the course of a… 
2000
2000
Design, synthesis and antihistaminic (H(1)) activity of some condensed 3-aminopyrimidin-4(3H)-ones.
1997
1997
Different mechanisms are responsible for the contractile effects of histaminergic compounds on isolated intestinal smooth muscle cells
Highly Cited
1994
Highly Cited
1994
Histamine-induced modulation of nociceptive responses
1994
1994
Calcium‐dependence of histamine‐ and carbachol‐induced inositol phosphate formation in human U373 MG astrocytoma cells: comparison with HeLa cells and brain slices
1 Histamine (1 mm) induced an accumulation of inositol monophosphate ([3H]‐IP1) in the U373 MG human astrocytoma cell line which… 
Review
1991
Review
1991
Pharmacokinetic interactions between theophylline and other medication (Part I).
  • R. Upton
  • Clinical pharmacokinetics
  • 1991
  • Corpus ID: 40711040
Many drugs have been found to increase or decrease the clearance of theophylline, probably by interaction with one or more of the… 
1990
1990
Metabolism of temelastine (SK&F 93944) in hepatocytes from rat, dog, cynomolgus monkey and man.
A species comparison of the metabolic pathways of temelastine has been made using hepatocyte preparations from rat, dog… 
Highly Cited
1986
Highly Cited
1986
Pharmacological studies with SK&F 93944 (temelastine), a novel histamine H1‐receptor antagonist with negligible ability to penetrate the central nervous system
1 SK&F 93944 (temelastine), a novel histamine H1‐receptor antagonist, has been studied in a variety of in vitro and in vivo test… 
1986
1986
Acute and subacute actions on human performance and interactions with diazepam of temelastine (SK&F93944) and diphenhydramine.
Thirteen healthy subjects participated in a combined acute and subacute double-blind, cross-over trial of two H1-antihistamines… 
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