temelastine

SummaryThirteen healthy subjects participated in a combined acute and subacute double-blind, crossover trial of two H1… Expand

Anovel series of condensed 3-amino-2-(substituted)methylpyrimidin-4(3H)-ones is reported with potential H(1) receptor… Expand

&NA; Because previous studies suggest an antinociceptive role for the neuromodulator histamine (HA) in the periaqueductal grey or… Expand

1 Histamine (1 mm) induced an accumulation of inositol monophosphate ([3H]‐IP1) in the U373 MG human astrocytoma cell line which… Expand

Many drugs have been found to increase or decrease the clearance of theophylline, probably by interaction with one or more of the… Expand

A species comparison of the metabolic pathways of temelastine has been made using hepatocyte preparations from rat, dog… Expand

The toxicity of temelastine 2-[4-(5-bromo-3-methylpyrid-2-yl)butylamino]-5-[(6-methylpyrid+ ++-3-yl) methyl]-4-pyrimidone a… Expand

Competition by the potent selective H1-receptor antagonist temelastine (SK & F 93944) with [3H]mepyramine binding to mouse cortex… Expand

1 SK&F 93944 (temelastine), a novel histamine H1‐receptor antagonist, has been studied in a variety of in vitro and in vivo test… Expand

Thirteen healthy subjects participated in a combined acute and subacute double-blind, cross-over trial of two H1-antihistamines… Expand