technetium Tc 99m diaminodithiol-benzovesamicol

Tribendimidine is a broad-spectrum anthelminthic available in China, which is currently being pursued for U.S. Food and Drug… Expand

Three new racemic vesamicol analogs were successfully prepared in good yields and high purity. All compounds were characterized… Expand

Molecular imaging of the vesicular acetylcholine transporter (VAChT) using positron emission tomography (PET) may provide… Expand

Diaminedithiol (DADT) or N-monosubstituted DADT is known to form lipophilic neutral chelates with technetium. As a result, they… Expand

The diaminodithiol (DADT) ligand has been conjugated to the neuromuscular blocking agent benzovesamicol (BVM) in the 5-position… Expand

Twenty-two neutral, lipid-soluble 99mTc complexes have been synthesized from diamine dithiol (DADT) ligands which vary in alkyl… Expand

Full experimental details are given for the preparation of [18F]fluoroethoxy-benzovesamicol, (−)-(2R, 3R)-trans-2-hydroxy-3-(4… Expand

Alkylpiperidinyl and alkylpyrrolidinyl 99mTc-DADT complexes were synthesized and tested for their ability to cross the BBB. Each… Expand

A new ligand, an N-p-iodophenethyl diaminodithiol (DADT-IPE), an anlog of N-isopropyl-p-iodoamphetamine (IMP), was synthesized… Expand

In an effort to develop new, clinically useful 99Tcm-diaminodithiol (99Tcm-DADT) complexes for the evaluation of regional… Expand