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tebufelone
Known as:
1-(3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)-5-hexyn-1-one
, 5-Hexyn-1-one, 1-(3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)-
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Alkynes
Phenols
Narrower (1)
NE 11740
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
QSAR study of dual cyclooxygenase and 5-lipoxygenase inhibitors 2,6-di-tert-butylphenol derivatives.
J. Ruiz
,
C. Pérez
,
R. Pouplana
Bioorganic & Medicinal Chemistry
2003
Corpus ID: 31645363
Highly Cited
1998
Highly Cited
1998
New cyclooxygenase-2/5-lipoxygenase inhibitors. 1. 7-tert-buty1-2,3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: discovery and variation…
J. Janusz
,
P. A. Young
,
+18 authors
R. Farmer
Journal of Medicinal Chemistry
1998
Corpus ID: 23171501
A series of 5-keto-substituted 7-tert-buty1-2,3-dihydro-3,3- dimethylbenzofurans (DHDMBFs) were prepared and evaluated as…
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1997
1997
Automated gas chromatography/tandem mass spectrometry with on-line chemical derivatization for the determination of tebufelone and two metabolites in human plasma.
R. Dobson
,
M. K. Dirr
,
B. L. Merkt
Journal of Mass Spectrometry
1997
Corpus ID: 38200060
An automated capillary gas chromatography/tandem mass spectrometry (GC/MS/MS) assay for the simultaneous quantitation of…
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1995
1995
Interspecies Scaling of Tebufelone Pharmacokinetic Data and Application to Preclinical Toxicology
C. Cruze
,
G. R. Kelm
,
M. Meredith
Pharmaceutical Research
1995
Corpus ID: 10860489
AbstractPurpose. Retrospective application of allometric scaling techniques to tebufelone, a nonsteroidal antiinflammatory agent…
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1994
1994
Automated gas chromatography/tandem mass spectrometry assay for tebufelone and a 13C,(18)O-labeled analog in plasma: applicabilityto absolute bioavailability determination.
R. Dobson
,
G. R. Kelm
,
D. M. Neal
Biological Mass Spectrometry
1994
Corpus ID: 25147616
An automated capillary gas chromatography/tandem mass spectrometry (GC/MS/MS) assay for the simultaneous quantitation of…
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1993
1993
Absorption, bioavailability, and pharmacokinetics of tebufelone in the rat.
W. Sietsema
,
G. R. Kelm
,
+6 authors
R. Farmer
Journal of Pharmacy and Science
1993
Corpus ID: 35763190
Tebufelone (NE-11740) is a member of the new di-tert-butylphenol class of anti-inflammatory agents. It exhibits good inhibitory…
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1993
1993
Compositions comprenant une dispersion solide de tebufelone
Gary Robert Kelm
,
Douglas Joseph Dobrozsi
1993
Corpus ID: 105300019
La presente invention se rapporte a des compositions sous forme galenique comprenant une dispersion solide qui constitue un…
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1991
1991
Antipyretic activity of tebufelone (NE-11740) in man.
J. Powell
,
M. P. Meredith
,
R. Vargas
,
F. Mcmahon
,
A. Jain
Agents and actions. Supplements
1991
Corpus ID: 19849317
Tebufelone (formerly NE-11740) is a member of the new class of di-tert-butyl-phenol anti-inflammatory agents. It has previously…
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1990
1990
Pharmaceutical compositions tebufelone.
G. R. Kelm
,
A. Bruns
1990
Corpus ID: 101475549
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