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taxane 13-alpha-hydroxylase activity

Known as: taxa-4(20),11-dien-5alpha-ol,NADPH:oxygen oxidoreductase (13alpha-hydroxylating), taxane 13a-hydroxylase activity, taxane 13alpha-hydroxylase activity 
Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-ol = H(2)O + NADP(+) + taxa-4(20),11-dien-5alpha,13alpha-diol. [EC:1.14.13… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
MicroRNA-331-3p inhibits proliferation and metastasis of ovarian cancer by targeting RCC2
Introduction Epithelial ovarian carcinoma (EOC) is one of the most lethal gynecologic malignancies, with a poor 5-year survival… 
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Review
2016
Review
2016
Abstract P4-12-01: Long term follow up of patients (pts) with HER2positive (H+) early stage breast cancer (ESBC) treated with trastuzumab (T)
Background. H+BC is an aggressive variant of BC with earlier and more frequent metastatic relapse than HER2 normal disease… 
Review
2014
Review
2014
Molecular alterations and emerging targets in castration resistant prostate cancer.
Prostate cancer is the most common malignancy in Western Europe, of which approximately 10-20% presents with advanced or… 
2013
2013
Abstract P2-15-01: Impact of adjuvant trastuzumab (AT) on survival in metastatic (M1) her2 positive breast cancer
Background: Recurrence rates have declined since AT was added to chemotherapy (chx) for her2+ early breast cancer (BC). This has… 
Review
2011
Review
2011
The changing therapeutic landscape of castration-resistant prostate cancer
Castration-resistant prostate cancer (CRPC) has a poor prognosis and remains a significant therapeutic challenge. Before 2010… 
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2011
2011
Blinded validation study of genomic predictions for survival following adjuvant sequential anthracycline-docetaxel chemotherapy with or without endocrine therapy.
1030 Background: The adjuvant chemotherapy +/- endocrine survival (ACES) predictor is a microarray-based genomic algorithm that… 
2007
2007
SS8-5 ホルモン抵抗性再燃前立腺癌 (HRPC) に対する Taxane 系抗癌剤、Estramustine、Carboplatin 併用化学療法 (TEC療法)(前立腺再燃癌の機序, 第95回日本泌尿器科学会総会)
2003
2003
New taxane diterpenoids from Taiwanese Taxus sumatrana.
Two new taxane diterpenoids, tasumatrols A (1) and B (2), have been isolated from extracts of the leaves and twigs of Taiwanese… 
2002
2002
Dantaxusins C and D, two novel taxoids from Taxus yunnanensis.
Two new taxane diterpenes, dantaxusin C (1) and dantaxusin D (2), were isolated from an ethanol extract of the aerial parts of… 
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