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tanomastat

Known as: (S)-3-[(4'-Chloro-4-biphenylyl)carbonyl]-2-[(phenylthio)methyl]propionic acid, 4-[4-(chlorophenyl)phenyl]-4-oxo-2S-(phenylthiomethyl) butanoic acid 
A biphenyl matrix metalloproteinase (MMP) inhibitor (MMPI) with potential antineoplastic activity. Tanomastat inhibits MMP-2, MMP-3, and MMP-9… Expand
National Institutes of Health

Papers overview

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2015
2015
Rho family GTPases (including Rac, Rho and Cdc42) collectively control cell proliferation, adhesion and migration and are of… Expand
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2015
2015
OBJECTIVE Azithromycin has become a standard of care in therapy of bronchiolitis obliterans following lung transplantation… Expand
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Review
2013
Review
2013
Matrix metalloproteinase (MMP) comprises a family of zinc-dependent endopeptidases that degrade various components of the… Expand
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Review
2013
Review
2013
Tumour invasion and metastasis have been recognized as major causal factors in the morbidity and mortality among cancer patients… Expand
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2010
2010
The present work describes the insilico prodrug designing of Tanomastat, a matrix metalloproteinase inhibitor. Tanomastat was… Expand
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Review
2008
Review
2008
Consolidation therapy is used in order to maximize the benefit of first-line therapy and to improve the progression-free and… Expand
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE BAY 12-9566 (tanomastat) is a biphenyl matrix metalloprotease inhibitor (MMPI) with antiangiogenic and antimetastatic… Expand
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2005
2005
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… Expand
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Review
2002
Review
2002
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… Expand
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2000
2000
BAY 12‐9566 (4‐[4‐(chlorophenyl)phenyl]‐4‐oxo‐2S‐(phenylthiomethyl) butanoic acid) is a newly developed, synthetic matrix… Expand
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