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talinolol

Known as: (+-)-N-cyclohexyl-N'-(4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)phenyl)urea, 1-(4-cyclohexylureidophenoxy)-2-hydroxy-3-tert-butylaminopropane 
 
National Institutes of Health

Papers overview

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2013
2013
PurposeSuperior bioavailability of BCS Class 2 compounds incorporated into SNEDDS was previously reported. This study aims to… Expand
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Highly Cited
2010
Highly Cited
2010
Bioavailability of talinolol, a beta(1)-adrenergic receptor antagonist, was enhanced by coadministration with grapefruit juice… Expand
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2008
2008
OBJECTIVES To evaluate whether ABCC2 gene polymorphisms are associated with expression and/or function of the efflux pump… Expand
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Highly Cited
2007
Highly Cited
2007
St John's wort (SJW) is known to induce cytochrome P450 (CYP) 3A4 and P-glycoprotein through pregnane X-receptor activation. Our… Expand
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Highly Cited
2005
Highly Cited
2005
OBJECTIVES Our objectives were to evaluate the effect of single and repeated grapefruit juice ingestion relative to water on the… Expand
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2005
2005
BACKGROUND AND OBJECTIVE Surfactants used in pharmaceutical formulations can modulate drug absorption by multiple mechanisms… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND AND METHODS The antiepileptic drug carbamazepine is known to be an inducer of cytochrome P450 (CYP) 3A4 after binding… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND AND OBJECTIVES A single-nucleotide polymorphism (SNP) of the human multidrug-resistance gene in wobble position of… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND P-Glycoprotein is an efflux pump in many epithelial cells with excretory function. It has been demonstrated that… Expand
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Highly Cited
2000
Highly Cited
2000
PURPOSE The objective of this study was a systematic characterization and evaluation of cell culture models based on mixtures of… Expand
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