t(9;22)

A translocation between chromosome 9 and chromosome 22 that may be associated with Philadelphia chromosome and increased susceptibility to several… (More)

Topic mentions per year

Topic mentions per year

1975-2017
0204019752017

Papers overview

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Highly Cited
2006
Highly Cited
2006
Imatinib mesylate (Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, the causal agent in chronic myelogenous… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE To compare pediatric and adult therapeutic practices in the treatment of acute lymphoblastic leukemia (ALL) in… (More)
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Highly Cited
2002
Highly Cited
2002
Chronic myelogenous leukemia (CML) is caused by expression of the BCR-ABL tyrosine kinase oncogene, the product of the t(9;22… (More)
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Highly Cited
2002
Highly Cited
2002
Blast crisis is the most advanced stage of chronic myelogenous leukemia (CML) and is highly refractory to therapy. CML is caused… (More)
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Highly Cited
2000
Highly Cited
2000
The hallmark of chronic myeloid leukemia (CML) is the BCR-ABL fusion gene, which is usually formed as a result of the t(9;22… (More)
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Highly Cited
1999
Highly Cited
1999
NAD(P)H:quinone oxidoreductase (NQO1) converts benzene-derived quinones to less toxic hydroquinones and has been implicated in… (More)
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Highly Cited
1999
Highly Cited
1999
The Cancer and Leukemia Group B (CALGB) has been conducting a prospective cytogenetic companion study (CALGB 8461) to all CALGB… (More)
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Highly Cited
1996
Highly Cited
1996
HE PHILADELPHIA (Ph) chromosome was the first T chromosomal abnormality associated with a specific malignant disease in humans… (More)
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Highly Cited
1990
Highly Cited
1990
The Philadelphia chromosome, widely implicated in human leukaemia, is the result of a reciprocal translocation t(9;22) (q34;q11… (More)
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Highly Cited
1988
Highly Cited
1988
The Philadelphia chromosome is present in more than 95% of chronic myeloid leukemia patients and 13% of acute lymphocytic… (More)
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