t(4;14)

A chromosomal translocation that involves the chromosomes 4 and 14.
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
We have used whole exome sequencing to compare a group of presentation t(4;14) with t(11;14) cases of myeloma to define the… (More)
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Highly Cited
2011
Highly Cited
2011
The multiple myeloma SET domain (MMSET) protein is overexpressed in multiple myeloma (MM) patients with the translocation t(4;14… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE Cytogenetics is an important prognostic parameter in multiple myeloma (MM). Patients presenting with either t(4;14) or… (More)
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Highly Cited
2005
Highly Cited
2005
The t(4;14) translocation that occurs uniquely in a subset (15%) of patients with multiple myeloma (MM) results in the ectopic… (More)
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Highly Cited
2004
Highly Cited
2004
The frequency and prognostic relevance of translocations t(11;14) and t(4;14), the most common translocations involving the… (More)
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Highly Cited
2004
Highly Cited
2004
We have previously shown that dysregulation of fibroblast growth factor receptor 3 (FGFR3) by the t(4;14) translocation is a… (More)
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Highly Cited
2003
Highly Cited
2003
This study analyzed the frequency and clinical significance of t(4;14)(p16;q32) in multiple myeloma (MM) among 208 patients with… (More)
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Highly Cited
1998
Highly Cited
1998
Previously we reported that a karyotypically silent t(4;14)(p16. 3;q32.3) translocation is present in about 25% of multiple… (More)
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Highly Cited
1998
Highly Cited
1998
Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of… (More)
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Highly Cited
1997
Highly Cited
1997
Dysregulation of oncogenes by translocation to the IgH locus (14q32) is a seminal event in the pathogenesis of B-cell tumours1… (More)
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