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t(4;11)

A cytogenetic abnormality that involves a translocation between chromosomes 4 and 11.
National Institutes of Health

Papers overview

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2016
2016
The t(4;11)(q21;q23) fuses mixed-lineage leukemia (MLL) to AF4, the most common MLL-fusion partner. Here we show that MLL fused… Expand
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Review
2015
Review
2015
Infant B-cell acute lymphoblastic leukemia (B-ALL) accounts for 10% of childhood ALL. The genetic hallmark of most infant B-ALL… Expand
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Highly Cited
2013
Highly Cited
2013
The Mixed Lineage Leukemia (MLL) protein is an important epigenetic regulator required for the maintenance of gene activation… Expand
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Highly Cited
2003
Highly Cited
2003
PURPOSE To compare pediatric and adult therapeutic practices in the treatment of acute lymphoblastic leukemia (ALL) in… Expand
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Review
1999
Review
1999
Prospective studies on the detection of minimal residual disease (MRD) in acute leukemia patients have shown that large-scale MRD… Expand
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Highly Cited
1999
Highly Cited
1999
To define prognostic factors in infant acute lymphoblastic leukemia (ALL), the outcome of 106 infants (age </=12 months) during 3… Expand
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Highly Cited
1996
Highly Cited
1996
A novel human gene, LAF-4, was isolated from a subtracted cDNA library that showed strong sequence similarity to AF-4, a gene… Expand
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Highly Cited
1992
Highly Cited
1992
The ALL-1 gene located at human chromosome 11 band q23 is rearranged in acute leukemias with interstitial deletions or reciprocal… Expand
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Highly Cited
1991
Highly Cited
1991
The t(4;11)(q21;q23) chromosomal abnormality was identified in 40 (2%) of 1,986 children with newly diagnosed acute lymphoblastic… Expand
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Highly Cited
1991
Highly Cited
1991
Chromosomal region 11q23 participates in a number of reciprocal translocations with specific regions of chromosomes 4, 9, 19, and… Expand
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